Results 191 to 200 of about 916,608 (346)

Biosynthetic pathway of ribothymidine in B. subtilis and M. lysodeikticus involving different coenzymes for transfer RNA and ribosomal RNA

, 1975
Wolfgang E. Schmidt, H.H. Arnold, H. Kersten   +2 more
openalex   +2 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Transfer RNA [PDF]

Trends in Biochemical Sciences, 1980
openaire   +2 more sources

Transfer RNA-derived fragments as novel biomarkers of the onset and progression of gastric cancer. [PDF]

Exp Biol Med (Maywood), 2023
Xie Y, Zhang S, Yu X, Ye G, Guo J.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Anticodon Engineered Transfer RNA (tRNA^SUAG) Inhibits Hepatitis B Virus Replication by Promoting the Degradation of Core Protein. [PDF]

Adv Sci (Weinh)
Yang X, Sun H, Luo Z, Zhang Q, Song Y, Li J, Liu X, Wang J.   +7 more
europepmc   +1 more source

Transfer RNA-Derived Small Non-Coding RNA: Dual Regulator of Protein Synthesis.

, 2019
Hak Kyun Kim
openalex   +2 more sources

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Transfer RNA and small molecule therapeutics for aminoacyl-tRNA synthetase diseases. [PDF]

FEBS J
Samuels TN, Wu F, Mahmood M, Abuzaid WA, Sun N, Moresco A, Siu VM, O'Donoghue P, Heinemann IU.   +8 more
europepmc   +1 more source

Sequences Intervening between the Core Packaging Determinants Are Dispensable for Maintaining the Packaging Potential and Propagation of Feline Immunodeficiency Virus Transfer Vector RNAs

, 2005
Farah Mustafa, Akela Ghazawi, Preethi Jayanth, Pretty Susan Phillip, Jahabar Ali, Tahir A. Rizvi   +5 more
openalex   +1 more source