Results 221 to 230 of about 902,030 (357)

Editorial: The genome's rising star: Transfer RNA-derived small fragments. [PDF]

Front Mol Biosci, 2022
Yan W.
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Targeting Fusobacterium nucleatum through chemical modifications of host-derived transfer RNA fragments. [PDF]

ISME J, 2023
Yang M, Dong PT, Cen L, Shi W, He X, Li J.   +5 more
europepmc   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Dysregulated transfer RNA-derived small RNAs as potential gastric cancer biomarkers. [PDF]

Exp Biol Med (Maywood)
Yuan J, Gu W, Xu T, Zhang Y, Shen L, Yan J, Guan X, Chu H, Yuan R, Ju S.   +9 more
europepmc   +1 more source

Transfer RNA-mediated restoration of potassium current and electrical correction in premature termination long-QT syndrome hERG mutants. [PDF]

Mol Ther Nucleic Acids, 2023
Blomquist VG, Niu J, Choudhury P, Al Saneh A, Colecraft HM, Ahern CA.   +5 more
europepmc   +1 more source

Hydrogen bonding in yeast phenylalanine transfer RNA.

, 1975
Gary J. Quigley, Andrew H.‐J. Wang, Nadrian C. Seeman, F. L. Suddath, Alexander Rich, Joel L. Sussman, S. H. Kim   +6 more
openalex   +1 more source

Base Composition Differences between Avian Myeloblastosis Virus Transfer RNA and Transfer RNA Isolated from Host Cells [PDF]

, 1971
Kurt Randerath, Leonard J. Rosenthal, Paul C. Zamecnik   +2 more
openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Editorial: Synthetic biology and therapeutic applications of transfer RNA. [PDF]

Front Genet
Söll D, O'Donoghue P, Heinemann IU.
europepmc   +1 more source