Results 291 to 300 of about 906,448 (355)

3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht, Majd Machour, Inbal Michael, Maria Bulatova, Janette Zavin, Shulamit Levenberg   +5 more
wiley   +1 more source

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source

Multiple regulatory roles of the transfer RNA-derived small RNAs in cancers. [PDF]

Genes Dis
Zhang Y, Gu X, Li Y, Huang Y, Ju S.
europepmc   +1 more source

The structure of transfer RNA

Progress in Biophysics and Molecular Biology, 1971
openaire   +2 more sources

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

Advanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez   +9 more
wiley   +1 more source

Plasma‐Treated Hydrogel for Combined RONS and Chemotherapy Delivery: A Proof‐of‐Concept In Ovo

Advanced Functional Materials, EarlyView.
This study explores plasma‐treated hydrogels (PTH) as a new way to deliver both reactive oxygen and nitrogen species and chemotherapy (Doxorubicin) directly to tumors. In ovo tests show effects after a single dose, especially in osteosarcoma tumors. Tumor weight decrease, and a resistance‐related protein is reduced.
Milica Živanić, Albert Espona‐Noguera, Angela Privat Maldonado, Patrik Matušů, Francesco Tampieri, Maria‐Pau Ginebra, Abraham Lin, Evelien Smits, Annemie Bogaerts, Cristina Canal   +9 more
wiley   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

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Transfer RNA and Aminoacyl Transfer RNA in Developing Rats

Neonatology, 1976
The total transfer RNA (tRNA) level in the liver, kidney, skeletal muscle and heart muscle of developing rats was determined by purification using (³H)tRNA as an internal standard. Liver and kidney contained almost twice as much tRNA per gram tissue as heart and skeletal muscle.
Edward E. McKee, Paul J. Fritz, Dai Kee Liu   +2 more
openaire   +3 more sources

Transfer RNAs and Transfer RNA Genes in Plants

Annual Review of Plant Physiology and Plant Molecular Biology, 1993
INTRODUCTION 14 CYTOSOLIC tRNAs ... .. 14 Organization of tRNA Genes in the Plant Nuclear Genome ......... 14 Intervening Sequences in Nuclear tRNA Genes 14 Transcription of Nuclear tRNA Genes and tRNA Processing 15 Plant Suppressor tRNAs 16 Cytokinin-Containing tRNAs ... ..... 17 CHLOROPLAST tRNAs ... ...... ... .... .........
J. H. Weil, A. Dietrich, L. Marechal-Drouard   +2 more
openaire   +2 more sources

Transfer RNA Modification

EcoSal Plus, 2005
Transfer RNA (tRNA) from all organisms on this planet contains modified nucleosides, which are derivatives of the four major nucleosides. tRNA from Escherichia coli/Salmonella enterica contains 31 different modified nucleosides, which are all, except for one (Queuosine[Q]), synthesized on an oligonucleotide ...
Glenn R. Björk, Tord G. Hagervall
openaire   +3 more sources