Results 31 to 40 of about 4,527,665 (350)

Alternative genetic code for amino acids and transfer RNA revisited

open access: yesBiomolecular Concepts, 2013
The genetic code is highly conserved among all organisms and its evolution is thought to be strictly limited. However, an increasing number of studies have reported non-standard codes in prokaryotic and eukaryotic genomes.
Hamashima Kiyofumi, Kanai Akio
doaj   +1 more source

Transfer RNA demethylase ALKBH3 promotes cancer progression via induction of tRNA-derived small RNAs

open access: yesNucleic Acids Research, 2018
Transfer RNA is heavily modified and plays a central role in protein synthesis and cellular functions. Here we demonstrate that ALKBH3 is a 1-methyladenosine (m1A) and 3-methylcytidine (m3C) demethylase of tRNA.
Zhuojia Chen   +9 more
semanticscholar   +1 more source

Long-read sequencing of benthophilinae mitochondrial genomes reveals the origins of round goby mitogenome re-arrangements

open access: yesMitochondrial DNA. Part B. Resources, 2019
Genetic innovation may be linked to evolutionary success, and indeed, the invasive round goby mitochondrial genome sequence carries two novel features not previously described in Benthophilinae.
Silvia Gutnik   +2 more
doaj   +1 more source

Tissue-specific differences in human transfer RNA expression. [PDF]

open access: yesPLoS Genetics, 2006
Over 450 transfer RNA (tRNA) genes have been annotated in the human genome. Reliable quantitation of tRNA levels in human samples using microarray methods presents a technical challenge.
Kimberly A Dittmar   +2 more
doaj   +1 more source

Liquid biopsy: an examination of platelet RNA obtained from head and neck squamous cell carcinoma patients for predictive molecular tumor markers

open access: yesExploration of Targeted Anti-tumor Therapy, 2023
Aim: Recently, a tumor cell-platelet interaction was identified in different tumor entities, resulting in a transfer of tumor-derived RNA into platelets, named further “tumor-educated platelets (TEP)”.
Lisa T. Huber   +9 more
doaj   +1 more source

Modifications and functional genomics of human transfer RNA

open access: yesCell Research, 2018
Transfer RNA (tRNA) is present at tens of millions of transcripts in a human cell and is the most abundant RNA in moles among all cellular RNAs. tRNA is also the most extensively modified RNA with, on an average, 13 modifications per molecule.
T. Pan
semanticscholar   +1 more source

Novel gene rearrangement in the complete mitochondrial genome of Telenomus remus (Hymenoptera: Scelionidae)

open access: yesMitochondrial DNA. Part B. Resources, 2021
The current study describes the complete mitochondrial genome (mitogenome) of an egg parasitoid wasp, Telenomus remus Nixon 1937. This mitogenome is 16,014 bp in length, consisting of 37 typical coding genes (13 protein-coding genes, 22 transfer RNA ...
Weiwei Li, Yunfei Wu, Bin Chen
doaj   +1 more source

Transfer RNA-derived small RNA: an emerging small non-coding RNA with key roles in cancer

open access: yesExperimental Hematology & Oncology, 2022
Transfer RNAs (tRNAs) promote protein translation by binding to the corresponding amino acids and transporting them to the ribosome, which is essential in protein translation.
Xinliang Gu   +5 more
doaj   +1 more source

ER Membrane Contact Sites: Key Platforms for Biogenesis of RNA-Containing Extracellular Vesicles

open access: yesContact, 2022
The mechanisms by which cytoplasmic cargoes such as RNAs are incorporated into extracellular vesicles (EVs) are poorly understood. In a recent article published in Developmental Cell, we describe a novel function of endoplasmic reticulum membrane contact
Bahnisikha Barman   +2 more
doaj   +1 more source

7-Methylguanosine Modifications in Transfer RNA (tRNA)

open access: yesInternational Journal of Molecular Sciences, 2018
More than 90 different modified nucleosides have been identified in tRNA. Among the tRNA modifications, the 7-methylguanosine (m7G) modification is found widely in eubacteria, eukaryotes, and a few archaea.
Chie Tomikawa
semanticscholar   +1 more source

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