Results 61 to 70 of about 1,133,805 (266)

Transfer Information Assessment in Diagnosis of Vasovagal Syncope Using Transfer Entropy

Entropy, 2019
The paper presents an application of Transfer Entropy (TE) to the analysis of information transfer between biosignals (heart rate expressed as R-R intervals (RRI), blood pressure (sBP, dBP) and stroke volume (SV)) measured during head up tilt testing ...
Katarzyna Buszko, Agnieszka Piątkowska, Edward Koźluk, Tomasz Fabiszak, Grzegorz Opolski   +4 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Test of Sum Rules in Nucleon Transfer Reactions

Physical Review Letters, 2012
The quantitative consistency of nucleon transfer reactions as a probe of the occupancy of valence orbits in nuclei is tested. Neutron-adding, neutron-removal, and proton-adding transfer reactions were measured on the four stable even Ni isotopes, with particular attention to the cross section determinations. The data were analyzed consistently in terms
Schiffr, J.P., Hoffman, C R, Kay, B.P., Clark, J.A., Deibel, C.M., Freeman, S J, Howard, A.M., Mitchell, Alan, Parker, P.D., Sharp, D.K., Thomas, J S   +10 more
openaire   +5 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Far transfer of retrieval-practice benefits: rule-based learning as the underlying mechanism

Cognitive Research
Benefits of self-testing for learning have been consistently shown for simple materials such as word lists learned by rote memorization. Considerably less evidence for such benefits exists for complex, more educationally relevant materials and its ...
Bertram Opitz, Veit Kubik
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Supine transfer test-induced changes in cardiac index predict fluid responsiveness in patients without intra-abdominal hypertension. [PDF]

BMC Anesthesiol, 2023
Zhao Z, Zhang Z, Liu J, Xia Z, Xing Q, Zhang Y, Zheng Y, Shen L, Lin Q, Gu D, Wang P, Zhang S, Li F, Zhu B.   +13 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Microscale search-based algorithm based on time-space transfer for automated test case generation

Complex & Intelligent Systems
Automated test case generation for path coverage (ATCG-PC) is a major challenge in search-based software engineering due to its complexity as a large-scale black-box optimization problem.
Yinghan Hong, Fangqing Liu, Han Huang, Yi Xiang, Xueming Yan, Guizhen Mai   +5 more
doaj   +1 more source