Results 11 to 20 of about 616,358 (307)

Tsc3 regulates SPT amino acid choice in Saccharomyces cerevisiae by promoting alanine in the sphingolipid pathway

Journal of Lipid Research, 2018
The generation of most sphingolipids (SPLs) starts with condensation between serine and an activated long-chain fatty acid catalyzed by serine palmitoyltransferase (SPT).
Jihui Ren, Essa M. Saied, Aaron Zhong, Justin Snider, Christian Ruiz, Christoph Arenz, Lina M. Obeid, Geoffrey D. Girnun, Yusuf A. Hannun   +8 more
doaj   +1 more source

Arginyltransferase, Its Specificity, Putative Substrates, Bidirectional Promoter, and Splicing-derived Isoforms [PDF]

, 2006
Substrates of the N-end rule pathway include proteins with destabilizing N-terminal residues. Three of them, Asp, Glu, and (oxidized) Cys, function through their conjugation to Arg, one of destabilizing N-terminal residues that are recognized directly by
Brower, Christopher S., Davydov, Ilia V., Hu, Rong-Gui, Kwon, Yong Tae, Sheng, Jun, Varshavsky, Alexander, Wang, Haiqing, Zhou, Jianmin   +7 more
core   +2 more sources

Glutathione Transferase (GST)-Activated Prodrugs

Pharmaceutics, 2013
Glutathione transferase (formerly GST) catalyzes the inactivation of various electrophile-producing anticancer agents via conjugation to the tripeptide glutathione.
Andrea Calderan, Paolo Ruzza
doaj   +1 more source

A novel class of CoA-transferase involved in short-chain fatty acid metabolism in butyrate-producing human colonic bacteria [PDF]

, 2005
Peer reviewedPublisher ...
Altschul, Asanuma, Ausubel, Barcenilla, Barker, Bennett, Blaut, Boynton, Buckel, Cleland, Cédric Charrier, Diez-Gonzalez, Donna Henderson, Duncan, Ewing, Ewing, Fischer, Garry J. Rucklidge, Gary J. Duncan, Gerhardt, Gordon, Harry J. Flint, Heider, Louis, Macfarlane, Mack, Martin D. Reid, Miller, Ochman, Pauline Young, Perkins, Petra Louis, Pryde, Rincon, Rustam I. Aminov, Scherf, Schweiger, Selmer, Skantar, Smith, Söhling, Sramek, Tung, Valentin, Valerie J. Russell, Walter, Wächtershäuser, Wiesenborn, Wilkins   +48 more
core   +1 more source

Inhibition of protein geranylgeranylation and farnesylation protects against graft-versus-host disease via effects on CD4 effector T cells

Haematologica, 2013
Despite advances in immunosuppressive regimens, acute graft-versus-host disease remains a frequent complication of allogeneic hematopoietic cell transplantation.
Anne-Kathrin Hechinger, Kristina Maas, Christoph Dürr, Franziska Leonhardt, Gabriele Prinz, Reinhard Marks, Ulrike Gerlach, Maike Hofmann, Paul Fisch, Jürgen Finke, Hanspeter Pircher, Robert Zeiser   +11 more
doaj   +1 more source

Substrate specificity provides insights into the sugar donor recognition mechanism of O-GlcNAc transferase (OGT). [PDF]

, 2013
O-Linked β-N-acetylglucosaminyl transferase (OGT) plays an important role in the glycosylation of proteins, which is involved in various cellular events.
Chen, Xi, Chen, Yi, Li, Lei, Liu, Pi, Liu, Xiaoyan, Ma, Xiaofeng, Muthana, Musleh M, Sun, Hong, Wang, Peng G, Yan, Hui, Zhang, Lianwen, Zhou, Feng   +11 more
core   +2 more sources

Characterization of Genes Involved in the Formation of Aroma Volatiles in "Charentais" Melon Fruit [PDF]

, 2004
Volatiles esters impart distinct characteristics to the fruit quality. "Charentais" cantaloupe melon (Cucumis melo "cantalupensis") is characterized by abundant sweetness and aromatic flavour.
El-Sharkawy, Islam, Flores, Francisco B., Latché, Alain, Manriquez, Daniel, Pech, Jean-Claude   +4 more
core   +1 more source

Murine terminal deoxynucleotidyl transferase: cellular distribution and response to cortisone [PDF]

, 1975
The mouse thymus contains two forms of terminal deoxynucleotidyl transferase (TdT) which are distinguishable by the salt concentration necessary to elute them from a phosphocellulose column, by their distrubtion among the thymocyte subpopulations, and by
Baltimore, David, Kung, Patrick C., McCaffrey, Ronald P., Silverstone, Allen E.   +3 more
core   +1 more source

Biosynthesis of retinal phospholipids: incorporation of radioactivity from labeled phosphorylcholine and cytidine diphosphate choline

Journal of Lipid Research, 1970
Phosphorylcholine-1,2-14C and choline-1,2-14C-labeled cytidine diphosphate choline are incorporated into lecithin by whole homogenates and particulate fractions of rat retina with optimal incorporation of label by the microsomal fraction.
J.G. SWARTZ, J.E. MITCHELL
doaj   +1 more source

Palmitoyl Transferase Activity of Lecithin Retinol Acyl Transferase [PDF]

Biochemistry, 2006
Lecithin retinol acyl transferase (LRAT) has the essential role of catalyzing the transfer of an acyl group from the sn-1 position of lecithin to vitamin A to generate all-trans-retinyl esters (tREs). In vitro studies had shown previously that LRAT also can exchange palmitoyl groups between RPE65, a tRE binding protein essential for vision, and tREs ...
Linlong, Xue, Wan Jin, Jahng, Deviprasad, Gollapalli, Robert R, Rando   +3 more
openaire   +2 more sources