Results 51 to 60 of about 3,457 (253)

Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders

open access: yesAdvanced Science, EarlyView.
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang   +22 more
wiley   +1 more source

Optimizing Telephone Psychotherapy Service Quality Based on Therapists' Experiences: A Qualitative Study [PDF]

open access: yesپژوهش‌های علوم شناختی و رفتاری
Given the increasing expansion of psychotherapy services delivered via telephone and the importance of ensuring the quality of these services, attention to the factors affecting their effectiveness is essential.This research aimed to explore and deeply ...
Fahimeh Bahonar, Mahya Sanieemanes
doaj   +1 more source

Advancing Dry Electroencephalography With Scalable, Soft, and Transcranial Magnetic Stimulation‐Compatible Ti3C2Tx MXene Electrodes for Research and Clinical‐Grade Applications

open access: yesAdvanced Science, EarlyView.
Dry soft Ti3C2Tx MXene electroencephalography (EEG) electrodes provide low impedance (2.1 ± 1.8 kΩ at 10 Hz), long‐term stability, and enable safe simultaneous EEG and transcranial magnetic stimulation (TMS). Across scalp sites, hair types, and recording paradigms, including steady state visual evoked potentials (SSVEP), clinical EEG, and mobile EEG ...
Sneha Shankar   +17 more
wiley   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

Transfer of Learning for Evidence-Based Practice in Psychology

open access: yesInternational Education Studies, 2020
The aim of this paper is to assess the transfer of learning of students from a master’s degree in psychology through observation of their skills in information assessment and intervention. The participants were 10 incoming students of a professional-aimed master’s program in psychology offered in a Mexican public university.
Ana L. Jiménez-Pérez   +1 more
openaire   +2 more sources

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

open access: yesAdvanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun   +11 more
wiley   +1 more source

Insomnia in Patients with Borderline Personality Disorder

open access: yesNature and Science of Sleep, 2021
Jakub Vanek,1 Jan Prasko,1– 3 Marie Ociskova,1 Frantisek Hodny,1 Michaela Holubova,4 Kamila Minarikova,1 Milos Slepecky,2 Vlastimil Nesnidal1 1Department of Psychiatry, Faculty of Medicine and Dentistry, University Palacky Olomouc, University ...
Vanek J   +7 more
doaj  

Direct Growth of Transparent Boron Nitride Neutron Shielding Layer for Space Window

open access: yesAdvanced Science, EarlyView.
Direct growth of sp2‐sp3 hybridized BN (HBN) on quartz, enabled by an h‐BN buffer, produces transparent and stable films up to 80 µm thick with high transmittance and strong neutron shielding, making HBN a promising candidate for space windows in long‐term lunar missions.
Dobin Kim   +15 more
wiley   +1 more source

EL VÍNCULO EDUCATIVO Y LOS PROCESOS DE LIGAZÓN EN EDUCACIÓN MEDIA BÁSICA: LAS VOCES DE DOCENTES Y ESTUDIANTES.

open access: yesDidáskomai, 2018
Esta investigación, realizada como tesis de la Maestría en Psicología y Educación (Facultad de Psicología, Udelar) y en diálogo con la línea de investigación Políticas educativas, currículum y enseñanza, coordinada por Eloísa Bordoli (Instituto de ...
Valeria Píriz
doaj  

Attitude of Psychiatric Providers towards Patients with Borderline Personality Disorder in Jammu and Kashmir

open access: yesNigerian Postgraduate Medical Journal
Background: Borderline Personality Disorder (BPD) is characterised by pervasive emotional instability and self-destructive behaviours, often presenting challenges for healthcare professionals.
Rajnish Raj   +10 more
doaj   +1 more source

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