Results 151 to 160 of about 123,008 (219)

Serum hepcidin and erythropoietin in relation to anemia in non-diabetic chronic kidney disease: a cross-sectional study. [PDF]

Sci Rep
Gamal M, Abdel-Rahman AM, Elwahab AA, Refaie H, El-Halawani SM, Mortada WL, Sobh M.   +6 more
europepmc   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Interference of iron deficiency in glycated hemoglobin testing and its clinical implications: a systematic review and meta-analysis. [PDF]

Biochem Med (Zagreb)
Souza EMC, Domingueti CP.
europepmc   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Brazilin From Biancaea sappan as a Multi-Target Candidate in Thalassaemia: Mechanistic Insights Into Iron Chelation, Antioxidant Activity, and Potential JAK2 Modulation. [PDF]

Clin Exp Pharmacol Physiol
Youngest R, Kamisah Y, Safitri R, Maskoen AM.   +3 more
europepmc   +1 more source

SPG4 Hereditary Spastic Paraplegia: From Etiology to Therapy

Movement Disorders, EarlyView.
Abstract Hereditary spastic paraplegias (HSPs) comprise a heterogeneous group of heritable neurodegenerative disorders resulting from mutations in a wide variety of genes. HSP locomotor symptoms include lower limb weakness and spasticity that arise from progressive degeneration of corticospinal axons projecting from the motor cortex to the distal ...
Emanuela Piermarini, Peter W. Baas
wiley   +1 more source

Ferritin and Soluble Transferrin Receptor Beyond Inflammation: Independent Associations with Fasting Glucose and Metabolic Syndrome in a Central Asian Cohort. [PDF]

Diagnostics (Basel)
Kaldarkhan D, Sadykova K, Oshibayeva A, Nuskabayeva G, Baimakhanova G, Raimova M, Alikulova N, Khamidova N, Isanova S, Azizkhojayeva D, Turmanbayeva A, Kemelbekov K.   +11 more
europepmc   +1 more source

Aptamer–Based Targeted Protein Degradation: Mechanistic Principles, Delivery Strategies, and Translational Opportunities

Medicinal Research Reviews, EarlyView.
ABSTRACT Targeted elimination of pathogenic proteins remains a fundamental challenge in therapeutic intervention, particularly for proteins considered “undruggable” by conventional inhibition‐based approaches. Aptamer–based targeted protein degradation (TPD) has emerged as a versatile strategy that leverages the high specificity, structural ...
Ambrin Malik, Suyeon Son, Jaesung Lee, Ki Soo Park   +3 more
wiley   +1 more source

Virus-induced vesicular acidification enhances HIV immune evasion. [PDF]

iScience
Yaple-Maresh ME, Flores-McGregor GG, Zimmerman GE, Chen C, Collins KL.   +4 more
europepmc   +1 more source