The multifaceted roles of lysosomes in cancer
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Factors Associated with Transport Instability and Outcome Deterioration During Interhospital Intensive Care Transfers of Patients with COVID-19 in Germany. [PDF]
Hannappel L +4 more
europepmc +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Triceps Motor Branch Transfers to the Infraspinatus and Teres Minor Motor Branches for Restoration of Shoulder External Rotation: A Cadaver Study. [PDF]
Veronesi BA +5 more
europepmc +1 more source
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source
Clinical Pregnancy Outcomes Following Blastocyst Transfer Using Media with Different Hyaluronan Concentrations:A Retrospective Cohort Study. [PDF]
Özel MK, Şahin F, Aşir F, Çetin MT.
europepmc +1 more source
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Prevalence and Characteristics of Potentially Avoidable Interhospital Transfers.
Mueller SK +7 more
europepmc +1 more source
Why condition cash transfers? A multimethod pilot study evaluating the conditioning of cash transfers for tuberculosis treatment. [PDF]
Forse R +17 more
europepmc +1 more source

