Results 241 to 250 of about 4,175,172 (359)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Interhospital transfer of older adults with thoracic injury in Türkiye: a nationwide study. [PDF]

BMC Geriatr
Deniz MS, Ciflik KB, Ozdemir Ciflik B, Yetik Aras A.   +3 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Electron Transfer, Proton Transfer, and Molecule Transfer: Chemical Engineering and beyond. [PDF]

Chem Bio Eng
Li S, Wu Z, Pang X, Shi Y, Dong X, Chen Y, Tao C, Zhang B, Wang J, Guo B, Lv K, Zhang S, Ma X, Wang R, Li Q, Ji J, Zhang S, Zhang R, He G, Pan F, Yang D, Wu H, Shi J, Jiang Z.   +23 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Nerve and Tendon Transfers After Cervical Spinal Cord Injury: A Systematic Review of Strength Outcomes in 959 Patients. [PDF]

J Hand Surg Glob Online
Bagdady K, Taritsa I, Frost M, DeYoung J, Franco M, Jagasia P, Li C, Ko J, Janes L.   +8 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

From Flying Surgeon to Permanent Hub: A Historical Vignette of Decentralised Neurosurgical Service Development in Rural East Coast Sabah. [PDF]

Malays J Med Sci
Yap TC, Tan SE, Yap WN, Melchior RG, Bong JN, Wan Mohd Azaharuddin WNS, Azlan MNNI, Zenian MS.   +7 more
europepmc   +1 more source

Testing Paternalism: Cash versus In-Kind Transfers

, 2014
J. Cunha
semanticscholar   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source