A PANoptosis‐Based Signature for Survival and Immune Predication in Glioblastoma Multiforme
ABSTRACT Objective PANoptosis is a concept of total cell death characterized by pyroptosis, apoptosis, and necroptosis. We aimed to explore the clinical significance of PANoptosis‐related genes (PARGs) in glioblastoma multiforme (GBM). Methods Expression profiles of GBM were downloaded from the XENA database as a training dataset to construct a ...
Jun Yang+4 more
wiley +1 more source
Distinct DNA repair pathways involving RecA and nonhomologous end joining in Mycobacterium smegmatis [PDF]
Mycobacterium smegmatis was used to study the relationship between DNA repair processes involving RecA and nonhomologous end joining (NHEJ). The effect of gene deletions in recA and/or in two genes involved in NHEJ (ku and ligD) was tested on the ability
Anna Brzostek+39 more
core +1 more source
Background The Agrobacterium vacuum (Bechtold et al 1993) and floral-dip (Clough and Bent 1998) are very efficient methods for generating transgenic Arabidopsis plants. These methods allow plant transformation without the need for tissue culture.
Ülker Bekir+3 more
doaj +1 more source
Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim+3 more
wiley +1 more source
Coexisting protist-bacterial community accelerates protein transformation in microcosm experiments
Proteins constitute the major portion of labile substances in the marine environment and are an important source of organic matter supporting marine ecosystems.
Ngo Vy Thao+4 more
doaj +1 more source
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua+5 more
wiley +1 more source
Efficiency and Characteristics of MICP in Environments with Elevated Salinity, Diminished Oxygen, and Lowered Temperature: A Microfluidics Investigation [PDF]
Microbially Induced Carbonate Precipitation (MICP) shows promise for enhancing soil strength, but environmental factors significantly affect its mechanisms. The feasibility of MICP in challenging conditions, such as the soil around piles in shallow seabeds during winter,characterized by high salinity, low oxygen, and cold temperatures,remains uncertain
arxiv +1 more source
The role of the N-acetylglucosamine phosphoenolpyruvate phosphotransferase system from Lactobacillus plantarum 8014 in the mechanism of action of glycocin F : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University, Manawatū, New Zealand [PDF]
The rise in antibiotic-resistant bacteria is becoming a severe public health problem because of the shortage of new antibiotics to combat existing resistant bacterial pathogens.
Bailie, Marc Alex
core
The Shigella flexneri OmpA amino acid residues 188EVQ190 are essential for the interaction with the virulence factor PhoN2 [PDF]
Shigella flexneri is an intracellular pathogen that deploys an arsenal of virulence factors promoting host cell invasion, intracellular multiplication and intra- and inter-cellular dissemination.
Ambrosi, Cecilia+9 more
core +1 more source
Genetic Transformation of Coleus blumei Benth. Using Agrobacterium
Efficiency in transformation of three hybrids of Coleus blumei using wild and mutant strains of Agrobacterium sp. was evaluated. Successful transformation depended on specific bacterial strain-plant genotype combination and co-cultivation treatment.
Nataša Bauer+3 more
doaj