Results 201 to 210 of about 470,402 (305)

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

Advanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade, Ashna A. Kumar, Samuel O. Nitschke, Paul Joyce, Elahe Minaei, Stephanie E. Reuter, Chelsea Penney, Holly Warren, Ruby Shepherd, Jeremy N. Dinoro, Gordon G. Wallace, Anthony Dosseto, Sameera Ansar, Naila Islam, Alistair Lochhead, George Sharbeen, Phoebe A. Phillips, Morteza Aghmesheh, Wayne J. Hawthorne, Kara L. Vine‐Perrow   +19 more
wiley   +1 more source

An Engineered Variant of <i>E. coli</i> Nissle 1917 with Enhanced Transformation Efficiency and Robustness. [PDF]

ACS Synth Biol
Gudi CR, Neilson WJ, Mansell TJ.
europepmc   +1 more source

Revisiting the Mechanisms Involved in Calcium Chloride Induced Bacterial Transformation

Frontiers in Microbiology, 2017
Azka Asif, Hareem Mohsin, Rabia Tanvir, Yasir Rehman   +3 more
doaj   +1 more source

Hierarchically Engineered Multi‐Enzyme Nanoreactors for in vitro Drug Biosynthesis and Pathway Transplantation Into Cells

Advanced Materials, EarlyView.
A hierarchically structured metal–organic framework (eMIL) is shown to host the complete six‐enzyme biosynthesis pathway for the anti‐cancer pigment violacein, reshaping reaction dynamics and multiplying in vitro yields. eMIL nanoreactors deliver this reconstituted bacterial multi‐protein system into mammalian cells, where cell‐derived substrates and ...
Ainur Sharip, Somayah S. Qutub, Manar M. Farooqui, Walaa Baslyman, Nida Khalfay, Lukman O. Alimi, Patricia Lopez Sanchez, Lingyun Zhao, Milena Chernyshevskaia, Giovanni Colombo, Niveen M. Khashab, Stefan T. Arold, Raik Grünberg   +12 more
wiley   +1 more source

Enhanced Diclofenac Biodegradation by Bacterial Strains and a Microbial Consortium from Activated Sludge: Toxicity Assessment and Insights into Microbial Community Dynamics. [PDF]

J Xenobiot
Lara-Moreno A, Rodriguez-Morillo B, Madrid F, Martin-Sanchez PM, Villaverde J, Mejías C, Alonso E, Santos JL, Morillo E.   +8 more
europepmc   +1 more source

Leaftronics: Bio‐Fractal Scaffolds From Leaf Venation for Low‐Waste Electronics

Advanced Materials, EarlyView.
“Leaftronics” transforms naturally evolved leaf venation into quasi‐fractal scaffolds for sustainable electronics. Polymer‐infiltrated leaf skeletons can be used to fabricate ultra‐smooth, reflow‐ and thin‐film‐compatible decomposable substrates, while making the same lignocellulose networks conducting results in flexible transparent electrodes.
Rakesh Rajendran Nair, Hrisheekesh Thachoth Chandran, Karl Leo, Hans Kleemann   +3 more
wiley   +1 more source

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

Advanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee, Moon‐Jo Kim, DongEung Kim, Chan Ho Moon, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Junhyub Jeon, Junhyuk Son, Munwon Lim, Minho Kang, Dong Yun Lee, Donghyun Lim, Jung‐Hoon Park, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Kisuk Yang, Yunho Jeong, Youngho Eom, Hyun‐Do Jung   +21 more
wiley   +1 more source

Radiation-Induced Synthesis of a Minocycline-Derived Polycyclic Scaffold with Anti-Inflammatory and Antibacterial Effects. [PDF]

Molecules
Jeong GH, Lee H, Kim TH, Chung BY, Lee SS, Bai HW.   +5 more
europepmc   +1 more source

Pulsed Electrolysis Prevents Sulfur Poisoning for Sustained Sulfide Valorization

Advanced Materials, EarlyView.
Integrating pulsed electrolysis with Sc‐doped NiFe‐LDH enables sustainable sulfide valorization, achieving >500 h stability, 99.8% efficiency. Moreover, this technology produces high‐purity sulfur and sodium formate, boosting profit by 121% to $1,294.7 per tonne of hydrogen.
Zhiyan Hou, Yangbo Ma, Yufeng Wu, Weijin Cao, Zhengxiao Guo, Changlong Wang   +5 more
wiley   +1 more source

<i>Streptococcus mitis</i> bacteriocins drive contact-dependent lysis of <i>S. pneumoniae</i> facilitating transformation in multispecies environments. [PDF]

mBio
Borralho J, Lança J, Bryton J, Antunes W, Sá-Leão R.   +4 more
europepmc   +1 more source