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Molecular mechanisms and applications of natural transformation in bacteria [PDF]

open access: yesFrontiers in Microbiology
Natural transformation is a process in which bacteria uptake exogenous DNA from the environment during a transient physiological state called competence.
Changcheng Niu   +8 more
doaj   +4 more sources

Natural transformation and cell division delay in competent Staphylococcus aureus [PDF]

open access: yesMicrobiology Spectrum, 2023
Genetic competence for natural transformation, considered one of the three main mechanisms leading to horizontal gene transfer in bacteria, is able to promote evolution, through genomic plasticity, and foster antibiotic resistance and virulence factors ...
Fedy Morgene   +4 more
doaj   +2 more sources

Genetic modification of Streptococcus dysgalactiae by natural transformation [PDF]

open access: yesmSphere
Streptococcus dysgalactiae is an emerging human and animal pathogen. Functional studies of genes involved in virulence of S. dysgalactiae and other pyogenic group streptococci are often hampered by limited genetic tractability.
Marita Torrissen Mårli   +4 more
doaj   +2 more sources

Effect of Nutritional Determinants and TonB on the Natural Transformation of Riemerella anatipestifer [PDF]

open access: yesFrontiers in Microbiology, 2021
Riemerella anatipestifer is a gram-negative bacterium that is the first naturally competent bacterium identified in the family Flavobacteriaceae. However, the determinants that influence the natural transformation and the underlying mechanism remain ...
Li Zhang   +55 more
doaj   +2 more sources

Mixed-biofilm natural transformation assay reveals the presence of staphylococci in human environments that can transfer SCCmec to Staphylococcus aureus [PDF]

open access: yesmSphere
Methicillin-resistant Staphylococcus aureus (MRSA) is an important pathogen that causes healthcare-, community-, and livestock-associated infections. The methicillin resistance gene mecA is embedded in the mobile genetic element termed Staphylococcal ...
Mais Maree   +7 more
doaj   +2 more sources

Evolution of the Natural Transformation Protein, ComEC, in Bacteria

open access: yesFrontiers in Microbiology, 2018
Natural transformation enables the incorporation of exogenous DNA into host genomes and plays a fundamental role in the evolution of microbial populations.
Zachary T. Pimentel, Ying Zhang
doaj   +3 more sources

Surviving the storm: exploring the role of natural transformation in nutrition and DNA repair of stressed Deinococcus radiodurans [PDF]

open access: yesApplied and Environmental Microbiology
Deinococcus radiodurans, a natural transformation (NT)-enabled bacterium renowned for its exceptional radiation resistance, employs unique DNA repair and oxidative stress mitigation mechanisms as a strategic response to DNA damage.
Dhirendra Kumar Sharma   +2 more
doaj   +2 more sources

Novel Flp pilus biogenesis-dependent natural transformation

open access: yesFrontiers in Microbiology, 2015
Natural transformation has been described in bacterial species spread through nearly all major taxonomic groups. However, the current understanding of the structural components and the regulation of competence development is derived from only a few model
Angel eAngelov   +8 more
doaj   +3 more sources

HopE and HopD Porin-Mediated Drug Influx Contributes to Intrinsic Antimicrobial Susceptibility and Inhibits Streptomycin Resistance Acquisition by Natural Transformation in Helicobacter pylori

open access: yesMicrobiology Spectrum, 2022
Helicobacter pylori is a human pathogen competent for natural transformation. Intrinsic and acquired antibiotic resistance contribute to the survival and multiplication of H. pylori under antibiotics.
Yixin Liu   +13 more
doaj   +1 more source

Natural Competence in the Filamentous, Heterocystous Cyanobacterium Chlorogloeopsis fritschii PCC 6912

open access: yesmSphere, 2022
Lateral gene transfer plays an important role in the evolution of genetic diversity in prokaryotes. DNA transfer via natural transformation depends on the ability of recipient cells to actively transport DNA from the environment into the cytoplasm ...
Fabian Nies   +3 more
doaj   +1 more source

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