Results 41 to 50 of about 6,442,499 (284)

Natural transformation in Campylobacter species [PDF]

Journal of Bacteriology, 1990
Growing cells of Campylobacter coli and C. jejuni were naturally transformed by naked DNA without the requirement for any special treatment. Transformation frequencies for homologous chromosomal DNA were approximately 10(-3) transformants per recipient cell in C. coli and 10(-4) in C. jejuni.
Y, Wang, D E, Taylor
openaire   +2 more sources

Stabilizing Genetically Unstable Simple Sequence Repeats in the Campylobacter jejuni Genome by Multiplex Genome Editing: a Reliable Approach for Delineating Multiple Phase-Variable Genes

mBio, 2021
Hypermutable simple sequence repeats (SSRs) are major drivers of phase variation in Campylobacter jejuni. The presence of multiple SSR-mediated phase-variable genes encoding enzymes that modify surface structures, including capsular polysaccharide (CPS ...
Shouji Yamamoto, Sunao Iyoda, Makoto Ohnishi   +2 more
doaj   +1 more source

Photoredox catalytic asymmetric dearomative [3 + 2] cycloaddition of isoquinolines with enones

Nature Communications
Asymmetric dearomative photocycloaddition has emerged as a transformative strategy for the enantioselective construction of complex three-dimensional molecular architectures from simple planar aromatic precursors. While significant progress has been made
Jingjing Huo, Songwei Yang, Manman Kong, Miao Xi, Baokun Qiao, Zhiyong Jiang   +5 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

On descent for coalgebras and type transformations [PDF]

Categories and General Algebraic Structures with Applications, 2016
We find a criterion for a morphism of coalgebras over a Barr-exact category to be effective descent and determine (effective) descent morphisms for coalgebras over toposes in some cases.
Maurice Kianpi
doaj  

Earthworm symbiont Verminephrobacter eiseniae mediates natural transformation within the host egg capsules using type IV pili

Frontiers in Microbiology, 2014
The dense microbial communities commonly associated with plants and animals should offer many opportunities for horizontal gene transfer (HGT) through described mechanisms of DNA exchange including natural transformation.
SEANA Kelyn DAVIDSON, Glenn F. J. Dulla, Ruth A Go, David A Stahl, Nicolas ePinel   +4 more
doaj   +1 more source

Characterizing the Chemical Contaminants Diversity and Toxic Potential of Untreated Wastewater From a Drug Rehabilitation Hospital: Understanding Impact on Downstream Environment

Frontiers in Environmental Science, 2022
This study characterizes a total of 21 wastewater samples collected from Al Amal hospital, and aims to determine if untreated hospital wastewater may impose a potentially detrimental impact on the downstream municipal biological wastewater treatment ...
Fras Baasher, Tian-Nyu Wang, Muhammad Zulhelmi Bin Yusnan, Mohsen Alkahtani, Yasir M. Bashawri, Hamed Al Qarni, Pei-Ying Hong, Pei-Ying Hong, Pei-Ying Hong   +8 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Induction of TRIM22 promotes autophagy and apoptosis of colorectal cancer through reactive oxygen species generation

Journal of Translational Medicine
Background Colorectal cancer (CRC) is one of the most common causes of cancer-associated death worldwide, and a rapid increase in the incidence and mortality of CRC has been predicted with a marked trend in the younger age group.
Xiaoxuan Ma, Radhakrishnam Raju Ruddarraju, Yibing Li, Bingyan Shen, Haizhen Liu, Chaochao Ge, Naixin Peng, Lei Gao, Chaojie Wang, Guoyu Zhang, Fujun Dai, Xinrui Lv   +11 more
doaj   +1 more source

The gonococcal genetic island and type IV secretion in the pathogenic Neisseria

Frontiers in Cellular and Infection Microbiology, 2011
Eighty percent of Neisseria gonorrhoeae strains and some Neisseria meningitidis strains encode a 57 kb gonococcal genetic island (GGI). The GGI was horizontally acquired and is inserted in the chromosome at the replication terminus. The GGI is flanked by
Meghan E Ramsey, Katelynn L Woodhams, Joseph P Dillard   +2 more
doaj   +1 more source