Results 51 to 60 of about 6,442,499 (284)
Biomolecules, 2023 C. jejuni is an important food-borne pathogen displaying high genetic diversity, substantially based on natural transformation. The mechanism of DNA uptake from the environment depends on a type II secretion/type IV pilus system, whose components are ...
Julia C. Golz +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Chiral Brønsted acid-catalyzed kinetic resolution of radical additions
Nature CommunicationsKinetic resolution has been a cornerstone for accessing enantioenriched molecules, but its application in radical chemistry has remained elusive due to the high reactivity of radical intermediates. Here, we present a new approach enabling precise Kinetic
Cheng Luo +5 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Some categorical aspects of the inverse limits in ditopological context
Applied General Topology, 2018 This paper considers some various categorical aspects of the inverse systems (projective spectrums) and inverse limits described in the category ifPDitop, whose objects are ditopological plain texture spaces and morphisms are bicontinuous point functions
Filiz Yildiz
doaj +1 more source
Frontiers in Microbiology, 2021 Campylobacter is a major food-borne pathogen in humans, and previous studies reported a high prevalence of gentamicin-resistant Campylobacter isolates from food-producing animals in China.
Xiaoyan Zhang +7 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Other title: Office of Children Services Transformation initial findings report
, 2020 "February 2020."; "Mike DeWine, Governor of Ohio; Jon Husted, Lt. Governor of Ohio."; "Ohio Governor's Children's Initiative, Children Services Transformation."; "Safe children. Stable homes.
Ohio. Children Services Transformation Advisory Council
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source