Results 71 to 80 of about 584,987 (262)
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Paradoxes and the Nature of Ambidexterity in IT Transformation Programs
Information Systems Research, 2015 Though information technology (IT) transformation programs are gaining in importance, we know little about the nature of the challenges involved in such programs and how to manage them. Using grounded theory methodology, we conducted a multiyear case study of a large IT transformation program in a major commercial bank, during which we encountered the ...
Robert Wayne Gregory +3 more
openaire +2 more sources
Transformation of Rhizoctonia solani
, 2003 The aim of this study was to develop a genetic transformation system for the plant pathogenic fungus Rhizoctonia solani (teliomorph, Thanatephprus cucumeris Frank [Donk]). The availability of a transformation system would allow us to study gene exchange,
Wu, Jiang
core
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Avaliação da atenuação natural de hidrocarbonetos alifáticos clorados em um aquífero contaminado [PDF]
, 1999 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico.Este trabalho avalia os mecanismos de atenuação natural de hidrocarbonetos alifáticos clorados - CAHs em um aqüífero freático contaminado, de um aterro de resíduos ...
Cruz, Cristiane de Souza
core
Table_1_Genomics Approaches to Deciphering Natural Transformation in Cyanobacteria.xlsx
, 2019 Natural transformation is the process by which bacteria actively take up and maintain extracellular DNA. This naturally occurring process is widely used as a genetic modification method in bacterial species, and is crucial for the efficient genetic ...
Kristen E. Wendt (6811106) +1 more
core +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Urban Transformation as a tool for Disaster Mitigation [PDF]
Urban transformation projects are prepared with the purpose to sanitize decayed areas, to make cities beautiful and to create economic vitality. Since natural hazards threaten large metropolitan areas, urban transformation is pronounced together to ...
Handan Turkoglu, Seda Kundak
core
Brown's natural twisting cochain and the Eilenberg-Mac Lane transformation
, 1994 We construct a natural twisting cochain which commutes with the Eilenberg-Mac Lane natural ...
Morace, Frédéric, Prouté, Alain
core +1 more source