Results 121 to 130 of about 5,482,088 (343)

An economic assessment of banana genetic improvement and innovation in the Lake Victoria Region of Uganda and Tanzania: [PDF]

"This research report highlights findings from a set of studies undertaken by applied economists on the impact of improved banana cultivars and recommended management practices in the East African highlands.
Smale, Melinda, Tushemereirwe, Wilbeforce K.   +1 more
core  

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Genetic Transformation of Recalcitrant Cassava by Embryo Selection and Increased Hormone Levels

Methods and Protocols, 2018
Genetic engineering is considered to be an important tool for the improvement of cassava. Cassava is a highly heterozygous crop species for which conventional breeding is a lengthy and tedious process.
Ezequiel Matías Lentz, Sabrina Eisner, Emily Jane McCallum, Kim Schlegel, Francisco de Assis de Paiva Campos, Wilhelm Gruissem, Hervé Vanderschuren   +6 more
doaj   +1 more source

Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome.

Blood, 2013
Richter syndrome (RS) occurs in up to 15% of patients with chronic lymphocytic leukemia (CLL). Although RS, usually represented by the histologic transformation to a diffuse large B-cell lymphoma (DLBCL), is associated with a very poor outcome ...
E. Chigrinova, A. Rinaldi, I. Kwee, D. Rossi, P. Rancoita, J. Strefford, D. Oscier, K. Stamatopoulos, T. Papadaki, F. Berger, K. Young, F. Murray, R. Rosenquist, T. Greiner, W. Chan, E. Orlandi, M. Lucioni, R. Marasca, G. Inghirami, M. Ladetto, F. Forconi, S. Cogliatti, H. Votavova, S. Swerdlow, S. Stilgenbauer, M. Piris, A. Matolcsy, D. Spagnolo, E. Nikitin, A. Zamó, V. Gattei, G. Bhagat, G. Ott, E. Zucca, G. Gaidano, F. Bertoni   +35 more
semanticscholar   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

Optimizing Genetic Manipulation of Methanogens through Faster Cloning Techniques [PDF]

, 2018
Methanogenesis is the biological production of methane. Only anaerobic archaea known as methanogens are capable of such a metabolic feat. They have strict living conditions and substrate sources which determine their rate of metabolism.
Jennings, Merrisa
core   +2 more sources

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

FEBS Letters, EarlyView.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Exploring Agrobacterium-mediated genetic transformation methods and its applications in Lilium

Plant Methods
As a typical bulb flower, lily is widely cultivated worldwide because of its high ornamental, medicinal and edible value. Although breeding efforts evolved over the last 10000 years, there are still many problems in the face of increasing consumer demand.
Xinyue Fan, Hongmei Sun
doaj   +1 more source

Regeneration and Genetic Transformation in Eucalyptus Species, Current Research and Future Perspectives

Plants
Eucalyptus is an important plantation tree with a high economic value in China. The tree contributes significantly to China’s timber production. The stable and efficient Eucalyptus regeneration system and genetic transformation system are of great ...
Youshuang Wang, Zhihua Wu, Xiaoming Li, Xiuhua Shang   +3 more
doaj   +1 more source