Results 231 to 240 of about 1,102,835 (325)

On the analysis of metabolite quantitative trait loci: Impact of different data transformations and study designs. [PDF]

Sci Adv
Lee S, Kelly RS, Mendez KM, Prokopenko D, Hahn G, Lutz SM, Celedón JC, Clish CB, Weiss ST, Lange C, Lasky-Su JA, Hecker J, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium.   +12 more
europepmc   +1 more source

Genomics and genetic transformation in arachis. [PDF]

, 2018
ARAUJO, A. C. G., BRASILEIRO, A. C. M., GUIMARAES, P. M., LEAL BERTIOLI, S. C.   +3 more
core  

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Current Advancement and Future Prospects in Simplified Transformation-Based Plant Genome Editing. [PDF]

Plants (Basel)
Han X, Deng Z, Liu H, Ji X.
europepmc   +1 more source

Genetic Transformation in Crops [PDF]

, 2020
openaire   +2 more sources

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Success and limitations in adaptation of Fast-TrACC tissue culture-independent transformation in coffee, cotton, and tree tobacco. [PDF]

PLoS One
Negin B, Daniela Martin-Lesmes L, Jander G.   +2 more
europepmc   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source

Identification of <i>Nigrospora oryzae</i> Causing Leaf Spot Disease in Tomato and Screening of Its Potential Antagonistic Bacteria. [PDF]

Microorganisms
Zhang J, Yang F, Zhang A, Guo Q, Sun X, Zhang S, Di D.   +6 more
europepmc   +1 more source