Results 231 to 240 of about 5,482,088 (343)

Cytoduction Preserves Genetic Diversity Following Plasmid Transfer Into Pooled Yeast Libraries. [PDF]

Yeast
Jhuang HY, Aggeli D, Lang GI.
europepmc   +1 more source

Ubiquitin ligases in oncogenic transformation and cancer therapy

Nature Reviews. Cancer, 2017
D. Senft, Jianfei Qi, Z. Ronai
semanticscholar   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Molecular Features Accompanying Richter's Transformation in Patients with Chronic Lymphocytic Leukemia. [PDF]

Int J Mol Sci
Wang X, Chen J.
europepmc   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Experiment in Genetic Transformation

The American Biology Teacher, 1975
openaire   +1 more source

Mother transformer: A High-Throughput, Cost-Effective in Planta Hairy Root Transformation Method for Cannabis. [PDF]

BMC Biotechnol
Ajdanian L, Torkamaneh D.
europepmc   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Forage Crop Research in the Modern Age. [PDF]

Adv Sci (Weinh)
Liu Q, Huang G, Zhang Z, Lin Z, Deng X, Dong X, Liu Z, Wang Z, Zhang Y, Jing HC, Chong K, Cao X.   +11 more
europepmc   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source