PEG-Mediated Protoplast Transformation of <i>Penicillium sclerotiorum</i> (scaumcx01): Metabolomic Shifts and Root Colonization Dynamics. [PDF]
Jahan I+5 more
europepmc +1 more source
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source
Efficient <i>Agrobacterium</i>-Mediated Methods for Transient and Stable Transformation in Common and Tartary Buckwheat. [PDF]
Leite Dias S+3 more
europepmc +1 more source
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi+2 more
wiley +1 more source
A robust in-vitro and ex-vitro Agrobacterium rhizogenes-mediated hairy root transformation system in mungbean for efficient visual screening of transformants using the RUBY reporter. [PDF]
Kumar S+3 more
europepmc +1 more source
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
Leveraging CRISPR Cas9 RNPs and Cre-<i>loxP</i> in <i>Picochlorum celeri</i> for generation of field deployable strains and selection marker recycling. [PDF]
Burch TA, Krishnan A, Posewitz MC.
europepmc +1 more source
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran+3 more
wiley +1 more source
LINE1 insertion into the NACC2 locus disrupts the HDM2 axis and activates lung oncogenic signaling. [PDF]
Bojang P, Wang Y, Ramos KS.
europepmc +1 more source