Results 261 to 270 of about 1,102,835 (325)

Gene Editing in <i>Ganoderma lucidum</i>: Development, Challenges, and Future Prospects. [PDF]

J Fungi (Basel)
He S, Liu Y, Zhang Z, Cai M, Hao Y, Hu H.   +5 more
europepmc   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Advances in Genome Editing Through Haploid Induction Systems. [PDF]

Int J Mol Sci
Sheng H, Gao P, Yang C, Quilichini TD, Kochian LV, Datla R, Xiang D.   +6 more
europepmc   +1 more source

Profiling the effect of low frequency mechanical vibration on the metabolic and oxidative stress responses of A431 carcinoma

FEBS Open Bio, EarlyView.
20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti, Chikahiro Imashiro, Takashi Morikura, Shogo Miyata, Akira Funahashi, Kenjiro Takemura   +5 more
wiley   +1 more source

Establishing Halomonas as a chassis for industrial biotechnology: advances in synthetic biology tool development and metabolic engineering strategies. [PDF]

Microb Cell Fact
Coimbra AAB, Prakash S, Jiménez JI, Rios-Solis L.   +3 more
europepmc   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

FEBS Open Bio, EarlyView.
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada, Kouhei Ohtani, Pushpa Kiran Gullapalli, Kazuhiko Ishikawa   +3 more
wiley   +1 more source

Large DNA fragment ISEc9-mediated transposition during natural transformation allows interspecies dissemination of antimicrobial resistance genes. [PDF]

Eur J Clin Microbiol Infect Dis
Domingues S, Lima T, Escobar C, Plantade J, Charpentier X, da Silva GJ.   +5 more
europepmc   +1 more source

Multi-Omics and Functional Insights into Triterpenoid Biosynthesis Pathways in <i>Neopicrorhiza scrophulariiflora</i> (Pennell) D.Y.Hong. [PDF]

Plants (Basel)
Zhou P, Wang J, Li C, Li L, Duan L, Wang W, Liu X, Arshad KT, Liang Y, Zhao Y.   +9 more
europepmc   +1 more source

Development of a CRISPR-based cytosine base editor for restriction-modification system inactivation to enhance transformation efficiency in Vibrio Sp. dhg. [PDF]

J Biol Eng
Shon YJ, Baek D, Jin SB, Kim WJ, Jung GY, Lim HG.   +5 more
europepmc   +1 more source