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Genetic transformation of Drosophila with transposable element vectors.

Science, 1982
Exogenous DNA sequences were introduced into the Drosophila germ line. A rosy transposon (ry1), constructed by inserting a chromosomal DNA fragment containing the wild-type rosy gene into a P transposable element, transformed germ line cells in 20 to 50 ...
G. Rubin, A. Spradling
semanticscholar   +1 more source

Genetic transformation.

2011
Genetic transformation protocols are now available for all major grain legume crops. Nevertheless the majority of these species remain difficult to transform, mostly because they are recalcitrant for in vitro regeneration. This review aims to discuss the problems and achievements in grain legume regeneration and transformation and the factors affecting
Angenon, Geert, Tran, Thanh Thu
openaire   +1 more source

Clonal History and Genetic Predictors of Transformation Into Small-Cell Carcinomas From Lung Adenocarcinomas.

Journal of Clinical Oncology, 2017
Purpose Histologic transformation of EGFR mutant lung adenocarcinoma (LADC) into small-cell lung cancer (SCLC) has been described as one of the major resistant mechanisms for epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs ...
J. Lee   +22 more
semanticscholar   +1 more source

Genetic transformation of BCG

Tubercle, 1989
Two substrains of BCG, the Pasteur and Japanese, were successfully transformed with E. coli-mycobacteria shuttle plasmids, constructed from the E. coli plasmid, pIJ666 and the M. fortuitum plasmid, pAL5000. Individual plasmids (pYUB13, pYUB14) were obtained that contain selectable antibiotic resistance markers for kanamycin and chloramphenicol ...
Barry R. Bloom   +2 more
openaire   +3 more sources

Nanotechnology Strategies for Plant Genetic Engineering

Advances in Materials, 2021
Plant genetic engineering is essential for improving crop yield, quality, and resistance to abiotic/biotic stresses for sustainable agriculture. Agrobacterium‐, biolistic bombardment‐, electroporation‐, and poly(ethylene glycol) (PEG)‐mediated genetic ...
Yong Yan   +5 more
semanticscholar   +1 more source

Genetic transformation of mycobacteria [PDF]

open access: possibleTrends in Microbiology, 1993
Recent advances in methods for introducing DNA into both fast- and slow-growing species of mycobacteria have stimulated the construction of a variety of cloning vectors and the development of a versatile genetic system. These tools will facilitate studies of mycobacterial pathogenicity, antibiotic action and drug resistance, and lead to more effective ...
openaire   +2 more sources

Genetic Transformation of Switchgrass

2009
Switchgrass (Panicum virgatum L.) is a highly productive warm-season C4 species that is being developed into a dedicated biofuel crop. This chapter describes a protocol that allows the generation of transgenic switchgrass plants by Agrobacterium tumefaciens-mediated transformation. Embryogenic calluses induced from caryopses or inflorescences were used
Zeng-Yu Wang, Yajun Xi, Yaxin Ge
openaire   +3 more sources

Genetics of drug transformation

Clinical Biochemistry, 1986
Biotransformations of drugs are controlled or strongly affected by genetic factors. During the past few years several genetic deficiencies of drug-metabolizing reactions catalyzed by members of the family of cytochrome P-450 were observed. Choice of the appropriate drug to study and attention to urinary metabolites have been the essential ingredients ...
openaire   +3 more sources

The Genetics of Transformation

1961
Publisher Summary This chapter discusses the chemical nature of the transforming agent and mechanism of recombination occurring in transformation. The investigation of pneumococcal transformations was concerned largely with the chemical identification of the substance in the donor extract that was capable of inducing genetic transformations.
openaire   +3 more sources

Genetic Transformation of Rice

Critical Reviews in Plant Sciences, 1994
Abstract Rice was the first major monocot crop species to be transformed and regenerated. Initially, rice transformation was limited to japonica cultivars. Subsequently, a number of indica and javanica cultivars have also been transformed and regenerated into fertile transgenic plants.
Nicola M. Ayres, William D. Park
openaire   +2 more sources

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