Results 111 to 120 of about 3,035,887 (300)

Burden on the burdened: tuberculosis among Scheduled Tribes and non-Scheduled Tribes in constitutionally protected Scheduled and non-Scheduled areas of India

Infectious Diseases of Poverty
Background India accounts for over a quarter of the global tuberculosis (TB) burden. Among the most affected are India’s Scheduled Tribes (STs) communities, experiencing a disproportionately higher TB prevalence compared to non-STs.
Nishikant Singh, Sudheer Kumar Shukla, Ritam Dubey, Pratheeba John, Rituparna Sengupta, Ritesh Ranjan Pushkar, Navin Singh, Prince Chugh, Nishant Yadav, Rajeev Sadanandan   +9 more
doaj   +1 more source

The credibility transformer

European Actuarial Journal
Abstract Inspired by the large success of Transformers in Large Language Models, these architectures are increasingly applied to tabular data. This is achieved by embedding tabular data into low-dimensional Euclidean spaces resulting in similar structures as time-series data.
Salvatore Scognamiglio, Mario Wuthrich, Ronald Richman   +2 more
openaire   +5 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Critical sustainability events and perceived roles of academic leaders at a leading university in sustainability: CIT case study

Discover Sustainability
This case study explores the perceived roles of academic leaders in critical sustainability events at a leading university in sustainability—the University of Auckland (UoA). The UoA was selected because of its high position in the Times Higher Education
Anete Veidemane, Daniela Craciun, Barend van der Meulen   +2 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

“They make it seem harmless”: a qualitative investigation into women’s perceptions about novel gambling promotions and public relations strategies

BMC Public Health
Background The gambling industry uses a range of marketing strategies to increase the appeal and normalisation of their products. While there has been significant focus on how the gambling industry targets young men, there is evidence that the industry ...
Simone McCarthy, Hannah Pitt, Grace Arnot, Samantha L. Thomas   +3 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

‘I Battle With This Gambling Addiction Every Day’. Learning From Lived Experiences of Recovery to Guide Gambling Harm Prevention Strategies

Health Expectations
Background Gambling harm is a significant public health issue affecting individuals, families and communities. In Australia, gambling is deeply embedded within everyday life, supported by the widespread availability of gambling products and industry ...
Simone McCarthy, Hannah Pitt, Paul Fung, Margaret Potter, Grace Arnot, Samantha Thomas   +5 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Transformation [PDF]

Journal of Oncology Practice, 2012
John V, Cox, A Mark, Fendrick
openaire   +3 more sources