Results 121 to 130 of about 6,507,008 (334)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

High-throughput dataset of impurity adsorption on common catalysts in biomass upgrading applications

Scientific Data
An extensive dataset consisting of adsorption energies of pernicious impurities present in biomass upgrading processes on common catalysts and support materials has been generated.
Michelle A. Nolen, Sean A. Tacey, Martha A. Arellano-Treviño, Kurt M. Van Allsburg, Carrie A. Farberow   +4 more
doaj   +1 more source

WSCDL to WSBPEL: A Case Study of ATL-based Transformation [PDF]

, 2011
The ATLAS Transformation Language (ATL) is a hybrid transformation language that combines declarative and imperative programming elements and provides means to define model transformations. Most transformations using ATL reported in the literature show a
Ferreira Pires, Luis, Jansen, Slinger, Khadka, Ravi, Sapkota, Brahmananda, Sinderen, Marten van   +4 more
core   +1 more source

Aggregation-induced emission materials: a platform for diverse energy transformation and applications

, 2023
Xue Li, Hao Yang, Ping Zheng, Danmin Lin, Zhijun Zhang, Miaomiao Kang, Dong Wang, Ben Zhong Tang   +7 more
openalex   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

The role of alcohol consumption in the lives of older Australian women: qualitative insights and an agenda for further research, policy and practice

BMC Public Health
Background Alcohol consumption presents a threat to the health and wellbeing of women. The alcohol industry often pushes back at global efforts to prioritise the prevention of alcohol harms to women.
Simone McCarthy, Hannah Pitt, Kelli Benjamin, Julia Stafford, Danica Keric, Grace Arnot, Samantha Thomas   +6 more
doaj   +1 more source

A multimodal GeoAI approach to combining text with spatiotemporal features for enhanced relevance classification of social media posts in disaster response

Big Earth Data
Geo-referenced social media data supports disaster management by offering real-time insights through user-generated content. To identify critical information amid high volumes of noise, classifying the relevance of posts is essential.
David Hanny, Sebastian Schmidt, Shaily Gandhi, Michael Granitzer, Bernd Resch   +4 more
doaj   +1 more source

Spatial–Temporal Characteristics and Driving Mechanisms of Land–Use Transition from the Perspective of Urban–Rural Transformation Development: A Case Study of the Yangtze River Delta [PDF]

, 2022
Xing Niu, Fenghua Liao, Ziming Liu, Guancen Wu   +3 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source