Results 31 to 40 of about 1,392,091 (269)

Harnessing the potential of livestock agribusiness to address Africa’s youth bulge through decent employment and enhanced food security in a disrupted global landscape

Discover Sustainability
Africa’s youth bulge presents both a critical challenge and a transformative opportunity for sustainable development. With over 60% of the population under the age of 25 and youth unemployment averaging 33%, the continent urgently needs inclusive ...
Kefena Effa, Haile Deressa, Kassahun Teka, Amssalu Bezabeh, Negassi Ameha, Seid Mohammed, Fikru Regassa   +6 more
doaj   +1 more source

Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge, Maite E. Houwing, Rowena L. Grohssteiner, Ferdows Atiq, Sonja A. M. C. Teuben, Mirjam P. Fransen, Marjon H. Cnossen   +6 more
wiley   +1 more source

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte, Hannah Koch, Olivia A. Coughlin, Jillian R. Bouck, Allie Carter, Seethal A. Jacob   +5 more
wiley   +1 more source

The effectiveness of sedentary behaviour interventions on sitting time and screen time in children and adults: an umbrella review of systematic reviews

International Journal of Behavioral Nutrition and Physical Activity, 2020
Background There is increasing concern about the time people spend in sedentary behaviour, including screen time, leisure and occupational sitting. The number of both primary research studies (published trials) and reviews has been growing rapidly in ...
Phuong Nguyen, Long Khanh-Dao Le, Dieu Nguyen, Lan Gao, David W. Dunstan, Marj Moodie   +5 more
doaj   +1 more source

Ironic Medications: A Narrative‐Based Psycho‐Educational Intervention to Explore Patient–Provider Communication in Adolescents With Haematological Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with haematological malignancies face significant emotional and relational challenges, often accompanied by difficulties in communicating their needs within the healthcare context. To address these issues, a narrative‐based psycho‐educational intervention based on the creation and prescription of Ironic Medications was ...
Marta Stoppa, Elena Pagani Bagliacca, Selena Russo, Giulia Rampoldi, Maria Grazia Strepparava, Adriana Cristina Balduzzi, Andrea Biondi, Marco Spinelli   +7 more
wiley   +1 more source

Community based interventions for the primary prevention of cardiovascular disease in women living in rural, regional and remote areas: a scoping review

BMC Health Services Research
Background Cardiovascular disease (CVD) is the leading cause of death among women worldwide, yet prevention has historically centered on male risk profiles.
Madison Frith, Mary Rose Angeles, Feby Savira, Sean Randall, Crystal Man Ying Lee, Rachel Huxley, Suzanne Robinson   +6 more
doaj   +1 more source

Training for our digital future: a human-centered design approach to graduate medical education for aspiring clinician-innovators

npj Digital Medicine, 2018
In the current era of value-based healthcare with increasing emphasis on delivering higher quality care at lower costs, US healthcare innovation as a metric is at a premium. However, an implementation gap exists between technology-enabled innovations and
Jocelyn Carter, Yanik J. Bababekov, Maulik D. Majmudar   +2 more
doaj   +1 more source

A Single Amino Acid Switch in the Adenoviral DNA Binding Protein Abrogates Replication Center Formation and Productive Viral Infection

mBio, 2022
Adenoviruses are very efficient high-capacity vaccine vectors and are common gene delivery systems. Despite their extensive use in preclinical models and clinical trials over the past decades, adenoviral vectors still require optimization.
Jana Boddin, Wing-Hang Ip, Britta Wilkens, Konstantin von Stromberg, Wilhelm Ching, Emre Koyuncu, Luca D. Bertzbach, Thomas Dobner   +7 more
doaj   +1 more source

Assessing the financial burden of multimorbidity among patients aged 30 and above in India

BMC Health Services Research
Background Multimorbidity is associated with significant out-of-pocket expenditures (OOPE) and catastrophic health expenditure (CHE), especially in low- and middle-income countries like India.
Sudheer Kumar Shukla, Pratheeba John, Sakshi Khemani, Ankur Shaji Nair, Nishikant Singh, Rajeev Sadanandan   +5 more
doaj   +1 more source

Differential Regulation of Cellular FAM111B by Human Adenovirus C Type 5 E1 Oncogenes

Viruses, 2021
The adenovirus type 5 (HAdV-C5) E1 transcription unit encodes regulatory proteins that are essential for viral replication and transformation. Among these, E1A and E1B-55K act as key multifunctional HAdV-C5 proteins involved in various steps of the viral
Wing-Hang Ip, Britta Wilkens, Anastasia Solomatina, Judith Martin, Michael Melling, Paloma Hidalgo, Luca D. Bertzbach, Thomas Speiseder, Thomas Dobner   +8 more
doaj   +1 more source