Results 71 to 80 of about 1,241,486 (266)

The role of body composition in left ventricular remodeling, reverse remodeling, and clinical outcomes for heart failure with mildly reduced ejection fraction: more knowledge to the “obesity paradox”

open access: yesCardiovascular Diabetology
Background Although the “obesity paradox” is comprehensively elucidated in heart failure (HF) with reduced ejection fraction (HFrEF) and HF with preserved ejection fraction (HFpEF), the role of body composition in left ventricular (LV) remodeling, LV ...
Kang Fu   +7 more
doaj   +1 more source

The objects of transformation in higher education

open access: yes, 2008
This paper reviews the purposes of higher education in South Africa through to lens the 1997 Education White Paper. It is argued that, while the principles of the White Paper have shaped the development of the higher education system over the following ...
Hall, M
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Abdominal obesity in India: sex stratified multilevel estimates across 707 districts from a nationally representative cross-sectional survey

open access: yesScientific Reports
Abdominal obesity, measured using the waist-to-hip ratio, is an emerging public health concern in India, yet national averages mask important subnational variation relevant for local policy and prevention planning.
Pratheeba John   +8 more
doaj   +1 more source

Gewerkschaften und ostdeutsche Transformation

open access: yes
Die demokratische Revolution in der DDR und die anschließende politische, wirtschaftliche und gesellschaftliche Transformation stellten die Menschen in Ostdeutschland vor zahlreiche Herausforderungen, die bis heute nachwirken.

core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Identification of a Species of Pinnoctopus from the Red Sea (Cephalopoda: Octopodidae)

open access: yesSpecies Diversity
A species of octopus from the Red Sea is described based on two recently collected fisheries survey specimens and four historical specimens housed in the Natural History Museum, Vienna. The latter were collected between 1895 and 1927, including specimens
Sirajudheen Thayyil Kadengal   +6 more
doaj   +1 more source

Der Digital Transformation Canvas

open access: yes, 2018
Um KMU bei ihren Vorhaben zu unterstützen, hat der Projektleiter, Prof. Dr. Marc K. Peter, einen Canvas (eine Leinwand bzw. ein Raster) mit den zentralen Fragestellungen für die sieben Handlungsfelder erstellt.
Peter, Marc K.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Millet and Sorghum technology toolkit catalogue: Clearinghouse technical report series 014

open access: yes, 2023
This catalogue describes a suite of technologies related to the modernization of sorghum & millet production in Africa. It is based upon the combined efforts of the Project Platform for Agricultural Solutions (ProPAS), an information internet site, and ...
Technologies for African Agricultural Transformation
core  

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