Results 71 to 80 of about 312,679 (259)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Routine Testing–Oriented Method for Evaluating Inductive Current Transformers Accuracy Under Harmonic Distortion, Based on Maximum Current Error and Phase Displacement

IEEE Access
In the case of the modern inductive current transformers the most important factor that have influence on their wideband accuracy is the self-distortion of the secondary current caused by the nonlinearity of the magnetization characteristic of the ...
Michal Kaczmarek
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Operating Properties of the Inductive Current Transformer and Evaluation of Requirements for Its Compliance with the IEC 61869-1 WB2 Class Extension for Frequency up to 20 kHz

Energies
Nanocrystalline material provides an opportunity to improve the wideband performance of inductive current transformers and enables the possibility of ensuring their transformation accuracy for distorted and sinusoidal current from 50 Hz up to 20 kHz ...
Michal Kaczmarek
doaj   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Optimizing the accuracy of a rocket trajectory simulation by program transformation

Proceedings of the 12th ACM International Conference on Computing Frontiers, 2015
Static analysis by abstract interpretation is one of the most successful techniques used to over-approximate the roundoff errors in numerical programs. In our case, we are interested in using this method to improve the accuracy of programs which perform floating-point computations, known for their sensitivity to the way formulas are written.
Nasrine Damouche, Matthieu Martel, Alexandre Chapoutot   +2 more
openaire   +2 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Enhancing Forecast Accuracy: The Impact of Data Transformation in Time Series Models

Ekonometria
Aim: The aim of the article was formulate suggestions on which preprocessing method is preferable for various forecasting algorithms, including machine learning approaches, particularly for forecasting stock values.
Andrzej Dudek
doaj   +1 more source