Results 11 to 20 of about 171,516 (260)

Insights into the genetic influences of the microbiota on the life span of a host

open access: yesFrontiers in Microbiology, 2023
Escherichia coli (E. coli) mutant strains have been reported to extend the life span of Caenorhabditis elegans (C. elegans). However, the specific mechanisms through which the genes and pathways affect aging are not yet clear.
Fang Zhang   +11 more
doaj   +1 more source

Transcriptome analysis of activated charcoal-induced growth promotion of wheat seedlings in tissue culture

open access: yesBMC Genetics, 2020
Background Activated charcoal (AC) is highly adsorbent and is often used to promote seedling growth in plant tissue culture; however, the underlying molecular mechanism remains unclear.
Fu-shuang Dong   +9 more
doaj   +1 more source

Establishment of a Genetic Transformation System in Guanophilic Fungus Amphichorda guana

open access: yesJournal of Fungi, 2021
Fungi from unique environments exhibit special physiological characters and plenty of bioactive natural products. However, the recalcitrant genetics or poor transformation efficiencies prevent scientists from systematically studying molecular biological ...
Min Liang   +5 more
doaj   +1 more source

CRISPR/Cas9 in Planta Hairy Root Transformation: A Powerful Platform for Functional Analysis of Root Traits in Soybean

open access: yesPlants, 2022
Sequence and expression data obtained by next-generation sequencing (NGS)-based forward genetics methods often allow the identification of candidate causal genes. To provide true experimental evidence of a gene’s function, reverse genetics techniques are
Mohsen Niazian   +2 more
doaj   +1 more source

PheNominal: an EHR-integrated web application for structured deep phenotyping at the point of care

open access: yesBMC Medical Informatics and Decision Making, 2022
Background Clinical phenotype information greatly facilitates genetic diagnostic interpretations pipelines in disease. While post-hoc extraction using natural language processing on unstructured clinical notes continues to improve, there is a need to ...
James M. Havrilla   +8 more
doaj   +1 more source

Genetics of Transformed Follicular Lymphoma

open access: yesHemato, 2022
Histological transformation (HT) to a more aggressive disease–mostly diffuse large B-cell lymphoma–is considered one of the most dismal events in the clinical course of follicular lymphoma (FL).
Miguel Alcoceba   +6 more
doaj   +1 more source

Factors and Conditions That Impact Electroporation of Clostridioides difficile Strains

open access: yesmSphere, 2020
An important risk factor for acquiring Clostridioides difficile infection is antibiotic use. Therefore, a detailed knowledge of the physiology and the virulence factors can help drive the development of new diagnostic tools and nonantibiotic therapeutic ...
Disha Bhattacharjee, Joseph A. Sorg
doaj   +1 more source

Seminal plasma extracellular vesicles tRF-Val-AAC-010 can serve as a predictive factor of successful microdissection testicular sperm extraction in patients with non-obstructive azoospermia

open access: yesReproductive Biology and Endocrinology, 2022
Background There is a lack of biomarkers for distinguishing non-obstructive azoospermia (NOA) patients with successful sperm retrieval (Sp+) from those with failed sperm retrieval (Sp-).
Xiaoxiao Han   +10 more
doaj   +1 more source

Genetic Transformation in Yeasts [PDF]

open access: yesJournal of General Microbiology, 1974
SUMMARY: The transformability of 25 strains of yeasts belonging to 23 species in three genera - Saccharomyces, Hansenula and Candida - was investigated with respect to ten characters. Eighteen hour cultures at about the end of the log phase of growth, addition of 10 μg DNA/ml, and an incubation time of 30 min at 30 to 37 °C usually yielded best results.
N C, Khan, S P, Sen
openaire   +2 more sources

Efficient generation of recombinant influenza A viruses employing a new approach to overcome the genetic instability of HA segments. [PDF]

open access: yesPLoS ONE, 2015
Influenza A viruses (IAVs) are the most relevant and continual source of severe infectious respiratory complications in humans and different animal species, especially poultry.
Ahmed Mostafa   +5 more
doaj   +1 more source

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