Results 21 to 30 of about 462,471 (291)
Tomato: a crop species amenable to improvement by cellular and molecular methods [PDF]
Tomato is a crop plant with a relatively small DNA content per haploid genome and a well developed genetics. Plant regeneration from explants and protoplasts is feasable which led to the development of efficient transformation procedures.
A. Crossway +192 more
core +3 more sources
Targeted mutagenesis using CRISPR-Cas9 in the chelicerate herbivore Tetranychus urticae [PDF]
The use of CRISPR-Cas9 has revolutionized functional genetic work in many organisms, including more and more insect species. However, successful gene editing or genetic transformation has not yet been reported for chelicerates, the second largest group ...
Dermauw, Wannes +5 more
core +1 more source
An Evolutionary Reduction Principle for Mutation Rates at Multiple Loci [PDF]
A model of mutation rate evolution for multiple loci under arbitrary selection is analyzed. Results are obtained using techniques from Karlin (1982) that overcome the weak selection constraints needed for tractability in prior studies of multilocus event
A. Eyre-Walker +60 more
core +2 more sources
Multiple testing correction in linear mixed models. [PDF]
BackgroundMultiple hypothesis testing is a major issue in genome-wide association studies (GWAS), which often analyze millions of markers. The permutation test is considered to be the gold standard in multiple testing correction as it accurately takes ...
Eskin, Eleazar +3 more
core +2 more sources
Genetics of Transformed Follicular Lymphoma
Histological transformation (HT) to a more aggressive disease–mostly diffuse large B-cell lymphoma–is considered one of the most dismal events in the clinical course of follicular lymphoma (FL).
Miguel Alcoceba +6 more
doaj +1 more source
Factors and Conditions That Impact Electroporation of
An important risk factor for acquiring Clostridioides difficile infection is antibiotic use. Therefore, a detailed knowledge of the physiology and the virulence factors can help drive the development of new diagnostic tools and nonantibiotic therapeutic ...
Disha Bhattacharjee, Joseph A. Sorg
doaj +1 more source
Background There is a lack of biomarkers for distinguishing non-obstructive azoospermia (NOA) patients with successful sperm retrieval (Sp+) from those with failed sperm retrieval (Sp-).
Xiaoxiao Han +10 more
doaj +1 more source
Genetic Transformation in Yeasts [PDF]
SUMMARY: The transformability of 25 strains of yeasts belonging to 23 species in three genera - Saccharomyces, Hansenula and Candida - was investigated with respect to ten characters. Eighteen hour cultures at about the end of the log phase of growth, addition of 10 μg DNA/ml, and an incubation time of 30 min at 30 to 37 °C usually yielded best results.
N C, Khan, S P, Sen
openaire +2 more sources
Efficient generation of recombinant influenza A viruses employing a new approach to overcome the genetic instability of HA segments. [PDF]
Influenza A viruses (IAVs) are the most relevant and continual source of severe infectious respiratory complications in humans and different animal species, especially poultry.
Ahmed Mostafa +5 more
doaj +1 more source
Testicular Germ Cell Tumours: A Review of Genetics, Morphology and Immunohistochemistry [PDF]
Testicular Germ Cell Tumours (TGCTs) are rare tumours but they are the most common solid malignancy in young males and second leading cause of mortality. They exhibit biological diversity making them interesting for academics.
Kanwardeep Kaur Tiwana +4 more
doaj +1 more source

