Results 21 to 30 of about 462,471 (291)

Tomato: a crop species amenable to improvement by cellular and molecular methods [PDF]

open access: yes, 1989
Tomato is a crop plant with a relatively small DNA content per haploid genome and a well developed genetics. Plant regeneration from explants and protoplasts is feasable which led to the development of efficient transformation procedures.
A. Crossway   +192 more
core   +3 more sources

Targeted mutagenesis using CRISPR-Cas9 in the chelicerate herbivore Tetranychus urticae [PDF]

open access: yes, 2020
The use of CRISPR-Cas9 has revolutionized functional genetic work in many organisms, including more and more insect species. However, successful gene editing or genetic transformation has not yet been reported for chelicerates, the second largest group ...
Dermauw, Wannes   +5 more
core   +1 more source

An Evolutionary Reduction Principle for Mutation Rates at Multiple Loci [PDF]

open access: yes, 2010
A model of mutation rate evolution for multiple loci under arbitrary selection is analyzed. Results are obtained using techniques from Karlin (1982) that overcome the weak selection constraints needed for tractability in prior studies of multilocus event
A. Eyre-Walker   +60 more
core   +2 more sources

Multiple testing correction in linear mixed models. [PDF]

open access: yes, 2016
BackgroundMultiple hypothesis testing is a major issue in genome-wide association studies (GWAS), which often analyze millions of markers. The permutation test is considered to be the gold standard in multiple testing correction as it accurately takes ...
Eskin, Eleazar   +3 more
core   +2 more sources

Genetics of Transformed Follicular Lymphoma

open access: yesHemato, 2022
Histological transformation (HT) to a more aggressive disease–mostly diffuse large B-cell lymphoma–is considered one of the most dismal events in the clinical course of follicular lymphoma (FL).
Miguel Alcoceba   +6 more
doaj   +1 more source

Factors and Conditions That Impact Electroporation of Clostridioides difficile Strains

open access: yesmSphere, 2020
An important risk factor for acquiring Clostridioides difficile infection is antibiotic use. Therefore, a detailed knowledge of the physiology and the virulence factors can help drive the development of new diagnostic tools and nonantibiotic therapeutic ...
Disha Bhattacharjee, Joseph A. Sorg
doaj   +1 more source

Seminal plasma extracellular vesicles tRF-Val-AAC-010 can serve as a predictive factor of successful microdissection testicular sperm extraction in patients with non-obstructive azoospermia

open access: yesReproductive Biology and Endocrinology, 2022
Background There is a lack of biomarkers for distinguishing non-obstructive azoospermia (NOA) patients with successful sperm retrieval (Sp+) from those with failed sperm retrieval (Sp-).
Xiaoxiao Han   +10 more
doaj   +1 more source

Genetic Transformation in Yeasts [PDF]

open access: yesJournal of General Microbiology, 1974
SUMMARY: The transformability of 25 strains of yeasts belonging to 23 species in three genera - Saccharomyces, Hansenula and Candida - was investigated with respect to ten characters. Eighteen hour cultures at about the end of the log phase of growth, addition of 10 μg DNA/ml, and an incubation time of 30 min at 30 to 37 °C usually yielded best results.
N C, Khan, S P, Sen
openaire   +2 more sources

Efficient generation of recombinant influenza A viruses employing a new approach to overcome the genetic instability of HA segments. [PDF]

open access: yesPLoS ONE, 2015
Influenza A viruses (IAVs) are the most relevant and continual source of severe infectious respiratory complications in humans and different animal species, especially poultry.
Ahmed Mostafa   +5 more
doaj   +1 more source

Testicular Germ Cell Tumours: A Review of Genetics, Morphology and Immunohistochemistry [PDF]

open access: yesNational Journal of Laboratory Medicine, 2015
Testicular Germ Cell Tumours (TGCTs) are rare tumours but they are the most common solid malignancy in young males and second leading cause of mortality. They exhibit biological diversity making them interesting for academics.
Kanwardeep Kaur Tiwana   +4 more
doaj   +1 more source

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