Results 11 to 20 of about 462,471 (291)
Frontiers in Microbiology, 2022 Many studies shown that neurological diseases are associated with neural mitochondrial dysfunctions and microbiome composition alterations. Since mitochondria emerged from bacterial ancestors during endosymbiosis, mitochondria, and bacteria had analogous
Yao Zhu +6 more
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Insights into the genetic influences of the microbiota on the life span of a host
Frontiers in Microbiology, 2023 Escherichia coli (E. coli) mutant strains have been reported to extend the life span of Caenorhabditis elegans (C. elegans). However, the specific mechanisms through which the genes and pathways affect aging are not yet clear.
Fang Zhang +11 more
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BMC Genetics, 2020 Background Activated charcoal (AC) is highly adsorbent and is often used to promote seedling growth in plant tissue culture; however, the underlying molecular mechanism remains unclear.
Fu-shuang Dong +9 more
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Establishment of a Genetic Transformation System in Guanophilic Fungus Amphichorda guana
Journal of Fungi, 2021 Fungi from unique environments exhibit special physiological characters and plenty of bioactive natural products. However, the recalcitrant genetics or poor transformation efficiencies prevent scientists from systematically studying molecular biological ...
Min Liang +5 more
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Plants, 2022 Sequence and expression data obtained by next-generation sequencing (NGS)-based forward genetics methods often allow the identification of candidate causal genes. To provide true experimental evidence of a gene’s function, reverse genetics techniques are
Mohsen Niazian +2 more
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Roles of Candida albicans Mig1 and Mig2 in glucose repression, pathogenicity traits, and SNF1 essentiality. [PDF]
, 2020 Metabolic adaptation is linked to the ability of the opportunistic pathogen Candida albicans to colonize and cause infection in diverse host tissues. One way that C.
Filler, Scott G +7 more
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PheNominal: an EHR-integrated web application for structured deep phenotyping at the point of care
BMC Medical Informatics and Decision Making, 2022 Background Clinical phenotype information greatly facilitates genetic diagnostic interpretations pipelines in disease. While post-hoc extraction using natural language processing on unstructured clinical notes continues to improve, there is a need to ...
James M. Havrilla +8 more
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The molecular basis of T cell acute lymphoblastic leukemia [PDF]
, 2012 T cell acute lymphoblastic leukemias (T-ALLs) arise from the malignant transformation of hematopoietic progenitors primed toward T cell development, as result of a multistep oncogenic process involving constitutive activation of NOTCH signaling and ...
Adolfo Ferrando +23 more
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The EM Algorithm and the Rise of Computational Biology [PDF]
, 2010 In the past decade computational biology has grown from a cottage industry with a handful of researchers to an attractive interdisciplinary field, catching the attention and imagination of many quantitatively-minded scientists.
Citable Link +3 more
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Nucleosomes affect local transformation efficiency [PDF]
, 2012 Genetic transformation is a natural process during which foreign DNA enters a cell and integrates into the genome. Apart from its relevance for horizontal gene transfer in nature, transformation is also the cornerstone of today's recombinant gene ...
Aslankoohi, Elham +6 more
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