Results 281 to 290 of about 2,858,382 (405)

Editorial: Research advances on forest tree functional genomics and breeding. [PDF]

Front Plant Sci
Du J, Ye T, An Y, Chen Y, Wang J, Wang J, Lu M, Li Q.   +7 more
europepmc   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

The Potential of Transgenic Hybrid Aspen Plants with a Recombinant <i>Lac</i> Gene from the Fungus <i>Trametes hirsuta</i> to Degrade Trichlorophenol. [PDF]

Genes (Basel)
Vidyagina EO, Subbotina NM, Belova EN, Kovalitskaya YA, Evdokimov VA, Belyi VA, Kochetov AP, Surin AK, Krutovsky KV, Shestibratov KA.   +9 more
europepmc   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

Genetic connectivity of wolverines in western North America. [PDF]

Sci Rep
Day CC, Landguth EL, Sawaya MA, Clevenger AP, Long RA, Holden ZA, Akins JR, Anderson RB, Aubry KB, Barrueto M, Bjornlie NL, Copeland JP, Fisher JT, Forshner A, Gude JA, Hausleitner D, Heim NA, Heinemeyer KS, Hubbs A, Inman RM, Jackson S, Jokinen M, Kluge NP, Kortello A, Lacroix DL, Lamar L, Larson LI, Lewis JC, Lockman D, Lucid MK, MacKay P, Magoun AJ, McLellan ML, Moriarty KM, Mosby CE, Mowat G, Nietvelt CG, Paetkau D, Palm EC, Paul KJS, Pilgrim KL, Raley CM, Schwartz MK, Scrafford MA, Squires JR, Walker ZJ, Waller JS, Weir RD, Zeller KA.   +48 more
europepmc   +1 more source

A review of artificial intelligence in brachytherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen, Richard L. J. Qiu, Tonghe Wang, Shadab Momin, Xiaofeng Yang   +4 more
wiley   +1 more source

Comparative performance of novel viral landscape phylogeography approaches

Dellicour S, Gámbaro F, Jacquot M, Lequime S, Baele G, Gilbert M, Pybus OG, Suchard MA, Lemey P.   +8 more
europepmc   +1 more source

On the analysis of metabolite quantitative trait loci: Impact of different data transformations and study designs. [PDF]

Sci Adv
Lee S, Kelly RS, Mendez KM, Prokopenko D, Hahn G, Lutz SM, Celedón JC, Clish CB, Weiss ST, Lange C, Lasky-Su JA, Hecker J, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium.   +12 more
europepmc   +1 more source

Meta-analysis of exome array data identifies six novel genetic loci for lung function [version 3; referees: 2 approved] [PDF]

, 2018
et al,, Kraja, Aldi, Province, Michael A
core   +1 more source

Impact of enhanced leaf model on dose calculation accuracy in single‐isocenter multitarget stereotactic radiosurgery treatments

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Single‐isocenter multitarget (SIMT) radiosurgery has become increasingly popular as advancement in planning and delivery systems have made this approach clinically viable. With targets varying in size and distance from isocenter, SIMT plans are highly complex with dynamic multileaf collimator (MLC) motion.
Hem Moktan, Hongyu Jiang, H. Harold Li, Kenny Guida   +3 more
wiley   +1 more source