Results 21 to 30 of about 569,350 (369)

The molecular basis of T cell acute lymphoblastic leukemia [PDF]

open access: yes, 2012
T cell acute lymphoblastic leukemias (T-ALLs) arise from the malignant transformation of hematopoietic progenitors primed toward T cell development, as result of a multistep oncogenic process involving constitutive activation of NOTCH signaling and ...
Adolfo Ferrando   +23 more
core   +1 more source

Genetics of Transformed Follicular Lymphoma

open access: yesHemato, 2022
Histological transformation (HT) to a more aggressive disease–mostly diffuse large B-cell lymphoma–is considered one of the most dismal events in the clinical course of follicular lymphoma (FL).
Miguel Alcoceba   +6 more
doaj   +1 more source

The EM Algorithm and the Rise of Computational Biology [PDF]

open access: yes, 2010
In the past decade computational biology has grown from a cottage industry with a handful of researchers to an attractive interdisciplinary field, catching the attention and imagination of many quantitatively-minded scientists.
Citable Link   +3 more
core   +3 more sources

Genetic transformation of the dinoflagellate chloroplast [PDF]

open access: yeseLife, 2018
Coral reefs are some of the most important and ecologically diverse marine environments. At the base of the reef ecosystem are dinoflagellate algae, which live symbiotically within coral cells. Efforts to understand the relationship between alga and coral have been greatly hampered by the lack of an appropriate dinoflagellate genetic transformation ...
Adrian C. Barbrook   +11 more
openaire   +7 more sources

Seminal plasma extracellular vesicles tRF-Val-AAC-010 can serve as a predictive factor of successful microdissection testicular sperm extraction in patients with non-obstructive azoospermia

open access: yesReproductive Biology and Endocrinology, 2022
Background There is a lack of biomarkers for distinguishing non-obstructive azoospermia (NOA) patients with successful sperm retrieval (Sp+) from those with failed sperm retrieval (Sp-).
Xiaoxiao Han   +10 more
doaj   +1 more source

Automatic landmark annotation and dense correspondence registration for 3D human facial images [PDF]

open access: yes, 2012
Dense surface registration of three-dimensional (3D) human facial images holds great potential for studies of human trait diversity, disease genetics, and forensics.
Guo, Jianya, Mei, Xi, Tang, Kun
core   +1 more source

Factors and Conditions That Impact Electroporation of Clostridioides difficile Strains

open access: yesmSphere, 2020
An important risk factor for acquiring Clostridioides difficile infection is antibiotic use. Therefore, a detailed knowledge of the physiology and the virulence factors can help drive the development of new diagnostic tools and nonantibiotic therapeutic ...
Disha Bhattacharjee, Joseph A. Sorg
doaj   +1 more source

A genetic-algorithm-based method to find the unitary transformations for any de- sired quantum computation and application to a one-bit oracle decision problem [PDF]

open access: yesJ. Korean Phys. Soc. 65, 2001, 2014
We propose a genetic-algorithm-based method to find the unitary transformations for any desired quantum computation. We formulate a simple genetic algorithm by introducing the "genetic parameter vector" of the unitary transformations to be found. In the genetic algorithm process, all components of the genetic parameter vectors are supposed to evolve to
arxiv   +1 more source

Prenatal exposure to bisphenol AF induced male offspring reproductive dysfunction by triggering testicular innate and adaptive immune responses

open access: yesEcotoxicology and Environmental Safety, 2023
As an emerging endocrine-disrupting component with a chemical structure related to Bisphenol A (BPA), Bisphenol AF (BPAF) has become widely distributed in the environment and human surroundings.
Senlin Xue   +7 more
doaj  

Efficient generation of recombinant influenza A viruses employing a new approach to overcome the genetic instability of HA segments. [PDF]

open access: yesPLoS ONE, 2015
Influenza A viruses (IAVs) are the most relevant and continual source of severe infectious respiratory complications in humans and different animal species, especially poultry.
Ahmed Mostafa   +5 more
doaj   +1 more source

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