Results 21 to 30 of about 452,874 (322)

PheNominal: an EHR-integrated web application for structured deep phenotyping at the point of care

BMC Medical Informatics and Decision Making, 2022
Background Clinical phenotype information greatly facilitates genetic diagnostic interpretations pipelines in disease. While post-hoc extraction using natural language processing on unstructured clinical notes continues to improve, there is a need to ...
James M. Havrilla, Anbumalar Singaravelu, Dennis M. Driscoll, Leonard Minkovsky, Ingo Helbig, Livija Medne, Kai Wang, Ian Krantz, Bimal R. Desai   +8 more
doaj   +1 more source

Genetic Transformation in Pseudomonas [PDF]

Journal of General Microbiology, 1967
SUMMARY: Intraspecific and interspecific transformation in Pseudomonas has been investigated. Two isoleucine+valine requiring mutants of Pseudomonas aeruginosa have been transformed to prototrophy. By using gelatin liqui-faction as a marker character it was observed that two strains of P. fluorescens, a phytopathogen P.
N. C. Khan, S. P. Sen
openaire   +3 more sources

The molecular basis of T cell acute lymphoblastic leukemia [PDF]

, 2012
T cell acute lymphoblastic leukemias (T-ALLs) arise from the malignant transformation of hematopoietic progenitors primed toward T cell development, as result of a multistep oncogenic process involving constitutive activation of NOTCH signaling and ...
Adolfo Ferrando, Bash, Bash, Chen, Condorelli, Dube, Fisch, Hagemeijer, Hebert, Ho, Kelliher, Kikuchi, Larson, Lu, McGuire, McGuire, Nagel, Ntziachristos, Ntziachristos, Ono, Pieter Van Vlierberghe, Royer-Pokora, Rubnitz, van Grotel   +23 more
core   +1 more source

The EM Algorithm and the Rise of Computational Biology [PDF]

, 2010
In the past decade computational biology has grown from a cottage industry with a handful of researchers to an attractive interdisciplinary field, catching the attention and imagination of many quantitatively-minded scientists.
Citable Link, Jun S. Liu, Xiaodan Fan, Yuan Yuan   +3 more
core   +3 more sources

Genetic transformation of the dinoflagellate chloroplast [PDF]

eLife, 2018
Coral reefs are some of the most important and ecologically diverse marine environments. At the base of the reef ecosystem are dinoflagellate algae, which live symbiotically within coral cells. Efforts to understand the relationship between alga and coral have been greatly hampered by the lack of an appropriate dinoflagellate genetic transformation ...
Adrian C. Barbrook, Isabel C. Nimmo, R. Ellen R. Nisbet, Saul Purton, Ross F. Waller, Manuel Aranda, Jit Ern Chen, Jit Ern Chen, Katrin Geisler, Alison G. Smith, Christopher J. Howe, Imen Lassadi   +11 more
openaire   +7 more sources

Tomato: a crop species amenable to improvement by cellular and molecular methods [PDF]

, 1989
Tomato is a crop plant with a relatively small DNA content per haploid genome and a well developed genetics. Plant regeneration from explants and protoplasts is feasable which led to the development of efficient transformation procedures.
A. Crossway, A. Guri, A. Hoekema, A. Kinshara, A. Morgan, A. Zelcer, A.H. Paterson, A.J. Framond De, A.L. Phillips, A.L. Phillips, A.R. Krol Van der, B. Baker, B. Baker, B. Hause, B. McClintock, B. Piechulla, B.A. Levenko, B.D. Harrison, B.L. Ward, B.P. Moens, B.R. Thomas, B.R. Thomas, B.S. Gill, B.S. Landry, B.S. Landry, B.S. Landry, C. Chang, C. Pieterse, C. Waldron, C.D. Riggs, C.E. Vallejos, C.E. Vallejos, C.J.S. Smith, C.M. Rick, C.M. Rick, C.M. Rick, C.M. Rick, C.M. Rick, C.M. Rick, C.M. Rick, C.M. Rick, C.M. Smith, C.P. Meredith, D. Boer De, D. Botstein, D. Shah, D. Zamir, D. Zamir, D. Zamir, D.A. Evans, D.A. Evans, D.M. Barker, D.M. Lonsdale, D.P. Barlow, D.W. Barton, D.W. Galbraith, E. Haute Van, E. Pichersky, E.A. Frankenberger, E.A. Frankenberger, E.A. Shahin, E.A. Shahin, E.C. Tigchelaar, F.J. Zapata, G. Gavazzi, G. Melchers, G. Schweizer, G.S. Khush, G.S. Khush, H.P. Mühlbach, I. Negrutiu, I.M. Greenblat, J. Botterman, J. Haseloff, J. Hille, J. Hille, J. Paszkowski, J. Phillips, J. Wijbrandi, J.D. Palmer, J.D. Palmer, J.D. Palmer, J.D. Palmer, J.F. Gusella, J.F. Gusella, J.F. Shepard, J.G. Atherton, J.H. Hawkes, J.I. Yoder, J.J. Fillatti, J.L. Bennetzen, J.M. van Montagu Schell, J.S. Beckmann, J.S. Beckmann, J.W. Maxon-Smith, J.W. Verna De, Jacoues Hille, K. Ohyama, K. Shinozaki, K. Umesono, K.A. Darden, K.K. Kartha, L. Herrera-Estrella, L. Herrera-Estrella, L. Marton, L.A. Miki, L.P. Hosticka, L.W. Handley, M. Block De, M. Buiatti, M. Buiatti, M. Cuozzo, M. Jongsma, M. Koornneef, M. Koornneef, M. Mutschler, M. S. Ramanna, M. Sibi, M. Soller, M. Vaeek, M. Wallroth, M. Ziv, M.A. O'Connell, M.A. O'Connell, M.A. O'Connell, M.A. O'Connell, M.A. Sluys Van, M.A. Stevens, M.A. Stevens, M.D. Bennett, M.L.M.C. Tan, M.L.M.C. Tan, M.R. Hanson, M.S. Ramanna, M.S. Ramanna, M.S. Ramanna, M.W. Bevan, M.W. Ganal, M.Y. Menzel, Maarten Koornneef, N.A. Zagorska, N.D. Young, N.D. Young, N.E. Tumer, N.V. Federoff, P. Little, P. Zambryski, P.E. McClean, P.F. Ambros, P.G. Smith, P.J.M. Elzen Van den, P.J.M. Elzen Van den, P.M. Gresshoff, Pim Zabel, R. Bernatzky, R. Bernatzky, R. Ecochard, R. Hain, R. Niedz, R.A. Bressan, R.A.J. Daelen Van, R.B. Flavell, R.B. Horsch, R.D. Locky, R.D. Shillito, R.S. Nelson, R.T. Fraley, S. Dellaporta, S. McCormick, S. Ohki, S.D. Tanksley, S.D. Tanksley, S.D. Tanksley, S.D. Tanksley, S.D. Tanksley, S.D. Tanksley, St.G. Rogers, T. Helentjaris, T. Helentjaris, T. Helentjaris, T.C. Osborn, T.L. Adams, T.M. Klein, U. Wienand, V. Padmanabhan, V.A. Hilder, W. Gottschalk, W. Gruissem, W.L. Gerlach, W.R. Sharp, Y.S. Chyi, Z. Koukolikova-Nicola, Z. Tabaeizadeh   +192 more
core   +3 more sources

Seminal plasma extracellular vesicles tRF-Val-AAC-010 can serve as a predictive factor of successful microdissection testicular sperm extraction in patients with non-obstructive azoospermia

Reproductive Biology and Endocrinology, 2022
Background There is a lack of biomarkers for distinguishing non-obstructive azoospermia (NOA) patients with successful sperm retrieval (Sp+) from those with failed sperm retrieval (Sp-).
Xiaoxiao Han, Lin Hao, Zhenduo Shi, Ying Li, Liang Wang, Zhenbei Li, Qiang Zhang, Fangfang Hu, Yijuan Cao, Kun Pang, Zuobin Zhu   +10 more
doaj   +1 more source

Factors and Conditions That Impact Electroporation of Clostridioides difficile Strains

mSphere, 2020
An important risk factor for acquiring Clostridioides difficile infection is antibiotic use. Therefore, a detailed knowledge of the physiology and the virulence factors can help drive the development of new diagnostic tools and nonantibiotic therapeutic ...
Disha Bhattacharjee, Joseph A. Sorg
doaj   +1 more source

Efficient generation of recombinant influenza A viruses employing a new approach to overcome the genetic instability of HA segments. [PDF]

PLoS ONE, 2015
Influenza A viruses (IAVs) are the most relevant and continual source of severe infectious respiratory complications in humans and different animal species, especially poultry.
Ahmed Mostafa, Pumaree Kanrai, Henning Petersen, Sherif Ibrahim, Silke Rautenschlein, Stephan Pleschka   +5 more
doaj   +1 more source

Genetics of Transformed Follicular Lymphoma

Hemato, 2022
Histological transformation (HT) to a more aggressive disease–mostly diffuse large B-cell lymphoma–is considered one of the most dismal events in the clinical course of follicular lymphoma (FL).
Miguel Alcoceba, María García-Álvarez, Jessica Okosun, Simone Ferrero, Marco Ladetto, Jude Fitzgibbon, Ramón García-Sanz   +6 more
doaj   +1 more source