Results 41 to 50 of about 439,059 (350)

Kernel-based aggregation of marker-level genetic association tests involving copy-number variation [PDF]

open access: yes, 2013
Genetic association tests involving copy-number variants (CNVs) are complicated by the fact that CNVs span multiple markers at which measurements are taken. The power of an association test at a single marker is typically low, and it is desirable to pool
Breheny, Patrick, Li, Yinglei
core   +3 more sources

Genetic Transformation in Cryptococcus Species [PDF]

open access: yesJournal of Fungi, 2021
Genetic transformation plays an imperative role in our understanding of the biology in unicellular yeasts and filamentous fungi, such as Saccharomyces cerevisiae, Aspergillus nidulans, Cryphonectria parasitica, and Magnaporthe oryzae. It also helps to understand the virulence and drug resistance mechanisms of the pathogenic fungus Cryptococcus that ...
openaire   +3 more sources

A versatile Agrobacterium-based plant transformation system for genetic engineering of diverse citrus cultivars

open access: yesFrontiers in Plant Science, 2022
Developing an efficient transformation system is vital in genetically engineering recalcitrant crops, particularly trees. Here, we outline an Agrobacterium tumefaciens-based stable plant transformation methodology for citrus genetic engineering.
Michelle M. Dominguez   +4 more
doaj   +1 more source

An Evolutionary Reduction Principle for Mutation Rates at Multiple Loci [PDF]

open access: yes, 2010
A model of mutation rate evolution for multiple loci under arbitrary selection is analyzed. Results are obtained using techniques from Karlin (1982) that overcome the weak selection constraints needed for tractability in prior studies of multilocus event
A. Eyre-Walker   +60 more
core   +2 more sources

The history of Drosophila studies: steps in the development of genetics

open access: yesВавиловский журнал генетики и селекции, 2015
Experimental genetic studies of Drosophila were initiated by T.H. Morgan in 1910, when he discovered the sex-linked white-eyed mutation, white. This discovery commenced the transformation of Mendel’s “hereditary factors” to more specific but no less ...
N. N. Yurchenko   +2 more
doaj   +1 more source

Luteolin regulates the distribution and function of organelles by controlling SIRT1 activity during postovulatory oocyte aging

open access: yesFrontiers in Nutrition, 2023
The quality of oocytes determines their development competence, which will be rapidly lost if the oocytes are not fertilized at the proper time after ovulation.
Xupeng Xing   +17 more
doaj   +1 more source

Use of pre-transformation to cope with outlying values in important candidate genes [PDF]

open access: yes, 2010
Outlying values in predictors often strongly affect the results of statistical analyses in high-dimensional settings. Although they frequently occur with most high-throughput techniques, the problem is often ignored in the literature. We suggest to use a
Boulesteix, Anne-Laure   +2 more
core   +1 more source

Robust and Reproducible Agrobacterium-Mediated Transformation System of the C4 Genetic Model Species Setaria viridis

open access: yesFrontiers in Plant Science, 2020
Setaria viridis (green foxtail) has been identified as a potential experimental model system to genetically and molecularly characterise the C4 monocotyledonous grasses due to its small physical size, short generation time and prolific seed production ...
Duc Quan Nguyen   +4 more
doaj   +1 more source

The maintenance of sex in bacteria is ensured by its potential to reload genes

open access: yes, 2006
Why sex is maintained in nature is a fundamental question in biology. Natural genetic transformation (NGT) is a sexual process by which bacteria actively take up exogenous DNA and use it to replace homologous chromosomal sequences.
Derenyi, Imre   +2 more
core   +2 more sources

Geographic variation in walking activity in the red flour beetle Tribolium castaneum

open access: yesPopulation Ecology, EarlyView.
This study examined whether there is geographic variation in field populations, focusing on the moving activity in the red flour beetle Tribolium castaneum. Results showed significant differences in moving activity among field populations but no correlation with latitude or meteorological factors.
Kentarou Matsumura
wiley   +1 more source

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