Results 51 to 60 of about 452,874 (322)

Luteolin regulates the distribution and function of organelles by controlling SIRT1 activity during postovulatory oocyte aging

Frontiers in Nutrition, 2023
The quality of oocytes determines their development competence, which will be rapidly lost if the oocytes are not fertilized at the proper time after ovulation.
Xupeng Xing, Xupeng Xing, Jingfeng Peng, Jingfeng Peng, Jingyu Zhao, Jingyu Zhao, Ruoxi Shi, Ruoxi Shi, Caiqin Wang, Caiqin Wang, Zihan Zhang, Zihan Zhang, Zihan Wang, Zihan Wang, Zicong Li, Zicong Li, Zhenfang Wu, Zhenfang Wu   +17 more
doaj   +1 more source

Between Droughts and Floods: The Seasonal Response of Freshwater Snails in Artificial Reservoirs in the Brazilian Semiarid Region

Population Ecology, EarlyView.
We investigate the seasonal dynamics of two freshwater snails, Biomphalaria straminea and Melanoides tuberculata, in artificial reservoirs of the Brazilian semiarid region. Despite regulated hydrology, B. straminea exhibited strong seasonal fluctuations associated with dry periods, while M. tuberculata maintained stable populations throughout the year,
Lucas Henrique Sousa da Silva, João Hemerson de Sousa, Adriana Josefa da Rocha, Manuella Feitosa Leal, Lucas Ariel de Sousa Aguiar, Tamaris Gimenez Pinheiro, Edson Lourenço da Silva   +6 more
wiley   +1 more source

Preparation and evaluation of Brucella T4SS recombinant proteins in serodiagnosis of human brucellosis based on TMT-based proteomics technology

Frontiers in Cellular and Infection Microbiology
IntroductionBrucellosis, a significant zoonotic infectious disease, poses a global health threat. Accurate and efficient diagnosis is crucial for prevention, control, and treatment of brucellosis. VirB proteins, components of the Type IV secretion system
Qi Wu, Chen Sun, Liping Guo, Yujia Xie, Jinpeng Zhang, Jinpeng Zhang, Dehui Yin, Dehui Yin   +7 more
doaj   +1 more source

Infection Models for Pine Wilt Disease on the Basis of Vector Behaviors

Population Ecology, EarlyView.
Infection models for pine wilt disease without vector density were built to estimate the transmission coefficient of the pathogenic nematode. The models successfully simulated the annual change in the density of infected trees for four pine stands. ABSTRACT Pine wilt disease is caused by the pinewood nematode (Bursaphelenchus xylophilus Steiner et ...
Katsumi Togashi
wiley   +1 more source

Roles of Candida albicans Mig1 and Mig2 in glucose repression, pathogenicity traits, and SNF1 essentiality. [PDF]

, 2020
Metabolic adaptation is linked to the ability of the opportunistic pathogen Candida albicans to colonize and cause infection in diverse host tissues. One way that C.
Filler, Scott G, Huang, Manning Y, Lagree, Katherine, May, Gemma, McManus, C Joel, Mitchell, Aaron P, Solis, Norma V, Woolford, Carol A   +7 more
core   +3 more sources

Speciation Through the Lens of Population Dynamics: A Theoretical Primer on How Small and Large Populations Diverge

Population Ecology, EarlyView.
Population size and dynamics fundamentally shape speciation by influencing genetic drift, founder events, and adaptive potential. Small populations may speciate rapidly due to stronger drift, whereas large populations harbor more genetic diversity, which can alter divergence trajectories. We highlight theoretical models that incorporate population size
Ryo Yamaguchi, Hidaka Kubo, Tokuya Ogawa, Hayate Omura   +3 more
wiley   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

An Evolutionary Reduction Principle for Mutation Rates at Multiple Loci [PDF]

, 2010
A model of mutation rate evolution for multiple loci under arbitrary selection is analyzed. Results are obtained using techniques from Karlin (1982) that overcome the weak selection constraints needed for tractability in prior studies of multilocus event
A. Eyre-Walker, A. Fox, A. S. Kondrashov, A. S. Kondrashov, A. S. Kondrashov, B. Balkau, B. Charlesworth, B. Charlesworth, B. Charlesworth, C. F. Baer, C. Hoede, E. Deutsch, F. A. Kondrashov, F. Ababneh, F. Rodríguez, F. Squartini, I. M. Singer, J. F. C. Kingman, J. F. C. Kingman, J. H. Wilkinson, J. J. Duistermaat, J. Keilson, J. R. Munkres, K. E. Holsinger, K. E. Holsinger, K. Holsinger, K. V. Pylkov, L. A. Zhivotovsky, L. A. Zhivotovsky, L. Altenberg, L. Altenberg, Lee Altenberg, M. Iosifescu, M. Lynch, M. Lynch, M. W. Feldman, M. W. Feldman, M. W. Feldman, M. W. Feldman, M. W. Feldman, M. W. Hirsch, R. A. Horn, R. C. Lewontin, R. N. Brandon, R. Teague, S. Karlin, S. Karlin, S. Karlin, S. Karlin, S. Karlin, S. P. Otto, S. Whelan, U. Liberman, U. Liberman, V. Guillemin, V. Jayaswal, W. C. Salmon, W. C. Salmon, W. Feller, Z. Yang, Z. Yang   +60 more
core   +2 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Preparation and application of specific chicken yolk antibodies in detecting Brucella

Frontiers in Veterinary Science
Brucellosis, caused by Brucella, is a severe zoonotic disease. Conventional IgG antibody-based ELISA testing faces challenges such as false positives and cross-reactivity.
Xinru Qi, Shiqi Zhao, Qianhan Huang, Yun Wang, Qichuan Pei, Yixiao Chen, Dehui Yin, Dehui Yin, Tiansong Zhan, Tiansong Zhan   +9 more
doaj   +1 more source