Results 71 to 80 of about 2,898,627 (344)

Merkel cell polyomavirus activates LSD1-mediated blockade of non-canonical BAF to regulate transformation and tumorigenesis

open access: yesNature Cell Biology, 2020
Merkel cell carcinoma (MCC)—a neuroendocrine cancer of the skin—is caused by the integration of Merkel cell polyomavirus and persistent expression of large T antigen and small T antigen.
D. Park   +12 more
semanticscholar   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall   +2 more
wiley   +1 more source

PHILOSOPHY AND REVOLUTIONS IN GENETICS: DEEP SCIENCE AND DEEP TECHNOLOGY [PDF]

open access: yes, 2005
Series editor's preface -- Acknowledgements -- Introduction -- Ch. 1. Living organisms: their philosophical transformation form natural to artefactual beings -- Ch. 2. Philosophy, modern science and modern technology -- Ch. 3.
Lee, Keekok
core  

A comparative study of immune system based genetic algorithms in dynamic environments [PDF]

open access: yes, 2006
Copyright @ 2006 ACMDiversity and memory are two major mechanisms used in biology to keep the adaptability of organisms in the ever-changing environment in nature.
Yang, S   +2 more
core   +1 more source

The history of Drosophila studies: steps in the development of genetics

open access: yesВавиловский журнал генетики и селекции, 2015
Experimental genetic studies of Drosophila were initiated by T.H. Morgan in 1910, when he discovered the sex-linked white-eyed mutation, white. This discovery commenced the transformation of Mendel’s “hereditary factors” to more specific but no less ...
N. N. Yurchenko   +2 more
doaj   +1 more source

Perspectives on the Current and Future State of Artificial Intelligence in Medical Genetics

open access: yesAmerican Journal of Medical Genetics. Part A
Artificial intelligence (AI) is rapidly transforming numerous aspects of daily life, including clinical practice and biomedical research. In light of this rapid transformation, and in the context of medical genetics, we assembled a group of leaders in ...
Benjamin D. Solomon   +20 more
semanticscholar   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo   +5 more
wiley   +1 more source

Transformation of Rhizoctonia solani [PDF]

open access: yes, 2003
The aim of this study was to develop a genetic transformation system for the plant pathogenic fungus Rhizoctonia solani (teliomorph, Thanatephprus cucumeris Frank [Donk]). The availability of a transformation system would allow us to study gene exchange,
Wu, Jiang
core   +1 more source

An investigation of horizontal transfer of feed introduced DNA to the aerobic microbiota of the gastrointestinal tract of rats [PDF]

open access: yes, 2012
BACKGROUND: Horizontal gene transfer through natural transformation of members of the microbiota of the lower gastrointestinal tract (GIT) of mammals has not yet been described.
Raddadi Noura   +22 more
core   +1 more source

Genomic and Genetic Insights Into a Cosmopolitan Fungus, Paecilomyces variotii (Eurotiales)

open access: yesFrontiers in Microbiology, 2018
Species in the genus Paecilomyces, a member of the fungal order Eurotiales, are ubiquitous in nature and impact a variety of human endeavors. Here, the biology of one common species, Paecilomyces variotii, was explored using genomics and functional ...
Andrew S. Urquhart   +13 more
doaj   +1 more source

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