Results 61 to 70 of about 2,864,901 (314)

Incidence and Outcome of Infants With Cancer in Canada: A Report From Cancer in Young People in Canada Database

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Infants with cancer are rare and face unique challenges. Our study aims to describe the incidence of infantile cancers in Canada and to compare treatment‐related mortality (TRM) and their outcomes with those of older children. Methods We conducted a retrospective cohort study using the Cancer in Young People in Canada database ...
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Sylvia Cheng, Lesleigh Abbott, Tony Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Donna L. Johnston, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +22 more
wiley   +1 more source

Life cycle benzophenone 1 exposure induces anxiety- and depression-like behaviors in zebrafish via endoplasmic reticulum stress-mediated dopaminergic system dysfunction

Environmental Chemistry and Ecotoxicology
Environmental exposure to benzophenones (BPs) has emerged as a potential risk factor for the comorbidity of anxiety and depression. Among them, BP1 has attracted increasing attention due to its potential neurotoxic effects.
Zhipeng Qi, Peng Li, Xiang Gao, Qiuchen Wu, Keying Li, Zhuoyi Xie, Xilan Xia, Tianchen Wang, Xiangrong Zhou, Jianan Li, Xinying Zhao, Hui Yuan, Weiyi Song   +12 more
doaj   +1 more source

Genomic and Genetic Insights Into a Cosmopolitan Fungus, Paecilomyces variotii (Eurotiales)

Frontiers in Microbiology, 2018
Species in the genus Paecilomyces, a member of the fungal order Eurotiales, are ubiquitous in nature and impact a variety of human endeavors. Here, the biology of one common species, Paecilomyces variotii, was explored using genomics and functional ...
Andrew S. Urquhart, Stephen J. Mondo, Miia R. Mäkelä, James K. Hane, James K. Hane, Ad Wiebenga, Guifen He, Sirma Mihaltcheva, Jasmyn Pangilinan, Anna Lipzen, Kerrie Barry, Ronald P. de Vries, Igor V. Grigoriev, Alexander Idnurm   +13 more
doaj   +1 more source

Oncogenic NRAS Mutation in Incipient Sarcomatous Transformation of Cystic Nephroma From a Patient With DICER1‐Related Tumor Predisposition Syndrome

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Anaplastic sarcoma of the kidney (ASK) is a DICER1‐associated malignant tumor presumed to arise in a benign precursor, pediatric cystic nephroma (PCN). However, the initial oncogenic alteration(s) associated with malignant transformation are unknown.
Nahir Cortes‐Santiago, Sarah B. Whittle, Sarah Scollon, Sharon E. Plon, Sanjeev Vasudevan, Bryony J. Lucas, Angshumoy Roy   +6 more
wiley   +1 more source

Improved injection needles facilitate germline transformation of the buckeye butterfly Junonia coenia

BioTechniques, 2014
Germline transformation with transposon vectors is an important tool for insect genetics, but progress in developing transformation protocols for butterflies has been limited by high post-injection ova mortality.
Kahlia Beaudette, Tia M. Hughes, Jeffrey M. Marcus   +2 more
doaj   +1 more source

Luteolin regulates the distribution and function of organelles by controlling SIRT1 activity during postovulatory oocyte aging

Frontiers in Nutrition, 2023
The quality of oocytes determines their development competence, which will be rapidly lost if the oocytes are not fertilized at the proper time after ovulation.
Xupeng Xing, Xupeng Xing, Jingfeng Peng, Jingfeng Peng, Jingyu Zhao, Jingyu Zhao, Ruoxi Shi, Ruoxi Shi, Caiqin Wang, Caiqin Wang, Zihan Zhang, Zihan Zhang, Zihan Wang, Zihan Wang, Zicong Li, Zicong Li, Zhenfang Wu, Zhenfang Wu   +17 more
doaj   +1 more source

Merkel cell polyomavirus activates LSD1-mediated blockade of non-canonical BAF to regulate transformation and tumorigenesis

Nature Cell Biology, 2020
Merkel cell carcinoma (MCC)—a neuroendocrine cancer of the skin—is caused by the integration of Merkel cell polyomavirus and persistent expression of large T antigen and small T antigen.
D. Park, Jingwei Cheng, J. Mcgrath, Matthew Y. Lim, Camille H Cushman, Selene K Swanson, Michelle L. Tillgren, J. Paulo, P. Gokhale, L. Florens, M. Washburn, P. Trojer, J. Decaprio   +12 more
semanticscholar   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

Androgenetic Alopecia in Men: An Update On Genetics

Indian Journal of Dermatology
Androgenetic alopecia (AGA) is defined as the alopecia induced by androgens in genetically predisposed individuals. AGA results in progressive miniaturization of the hair follicles leading to vellus transformation of terminal hair.
I. Sadasivam, Ravikumar Sambandam, Damayandhi Kaliyaperumal, J. Dileep   +3 more
semanticscholar   +1 more source

First‐generation genome editing in potato using hairy root transformation

Plant Biotechnology Journal, 2020
Summary Genome editing and cis‐gene breeding have rapidly accelerated crop improvement efforts, but their impacts are limited by the number of species capable of being genetically transformed.
Nathaniel M. Butler, S. Jansky, Jiming Jiang   +2 more
semanticscholar   +1 more source