Results 101 to 110 of about 3,280,020 (335)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

TechStartUpGame: A serious game for training tech start-ups using AI-generated scenarios

Discover Education
This paper examines the possibility of combining serious games with AI-generated scenarios to improve education and training for tech startups. In the ever-changing and highly competitive field of entrepreneurship, it is crucial to adopt innovative ...
Rose Oluwaseun Adetunji, Abejide Ade-Ibijola   +1 more
doaj   +1 more source

Central twisted transformation groups and group $C^*$-algebras of central group extensions [PDF]

, 2002
We examine the structure of central twisted transformation group \cs-algebras $C_{0}(X)\rtimes_{\id,u}G$, and apply our results to the group \cs-algebras of central group extensions.
Dana, P. Williams, Siegfried Echterhoff
core   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Systems of advance-delay differential-difference equations and transformation groups

Electronic Journal of Differential Equations, 2016
A linear system of mixed-type differential difference equations is studied. A step derivation method and some conditions on an initial function are used to guarantee existence, uniqueness and smoothness of the solution.
Serguei I. Iakovlev, Valentina Iakovleva
doaj  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Disjointness in Transformation Groups [PDF]

Proceedings of the American Mathematical Society, 1972
In this paper, we shall be concerned with the question of what conditions on minimal transformation groups will guarantee that they are disjoint. Generalizing a result of I. Bronstein about lifting of minimality through group extensions to associated bitransformation groups, we prove that in a large class of transformation groups, disjointness is ...
openaire   +1 more source

Digital Transformation as a Competitive Factor in Supply Chain Management: Proof of Concept in One of the Largest Editorial Groups in Portugal [PDF]

, 2021
Sofia Carujo, João Rocha Santos, Pedro Fernandes da Anunciação   +2 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Some special transformation groups [PDF]

Proceedings of the American Mathematical Society, 1960
The proof uses some elementary vector-valued integration, the fact that on compact groups one has approximate identities consisting of trigonometric polynomials (by the Peter-Weyl and StoneWeierstrass theorems), as well as one conceivably new (but trivial) fact (?1, Lemma). Thus our arguments will be rather conventional.
openaire   +1 more source