Results 121 to 130 of about 3,280,020 (335)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Early adolescents’ visions of the future: towards hopeful and sustainable futures?

open access: yesFrontiers in Education
Education for Sustainable Development (ESD) particularly emphasises developing future-thinking competencies. Nevertheless, this line of thinking still represents a challenge for younger students, who tend to be left behind when deciding and visualising ...
Andrea Corres   +3 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Isotropy group on some topological transformation group structures

open access: yesМатематичні Студії
This paper explores the topological properties of irresolute topological groups, their quotient maps, and the role of topology in normal subgroups. It provides a detailed analysis\linebreak using examples and counterexamples.
D. Keerthana, V. Visalakshi
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Screening for intrinsic capacity and frailty in older adults with multimorbidity in the primary care setting: application of the ICOPE tool and two frailty instruments

open access: yesBMC Geriatrics
Background Intrinsic capacity (IC) co-exists with frailty and multimorbidity in primary care and guidelines recommend screening for IC and frailty to improve health outcomes.
Sai Zhen Sim   +6 more
doaj   +1 more source

The Body as a Tool for Demanding Climate Action and Justice

open access: yesSocial Inclusion
The escalating frequency and intensity of natural disasters underscore the urgency of the climate crisis. Against this backdrop, the global climate movement has surged, amplifying awareness of the climate emergency and pressuring governments and ...
Margaret Tilk   +2 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy