Results 81 to 90 of about 3,193,435 (364)

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

FEBS Letters, EarlyView.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause, Musalula Sinkala, Raj Ramesar   +2 more
wiley   +1 more source

Understanding the Implementation of Airbnb in Urban Contexts: Towards a Categorization of European Cities

Land, 2020
The sharing economy has experienced exponential growth in recent years, especially in the short-term rentals (STRs) tourist accommodation sector. This growth has caused disruptive effects in rural and urban contexts, especially in highly touristic cities.
Laura Serrano, Antonio Sianes, Antonio Ariza-Montes   +2 more
doaj   +1 more source

Generalized Central Limit Theorem and Renormalization Group

, 2010
We introduce a simple instance of the renormalization group transformation in the Banach space of probability densities. By changing the scaling of the renormalized variables we obtain, as fixed points of the transformation, the L\'evy strictly stable ...
A. Einstein, B.V. Gnedenko, B.V. Gnedenko, D. Castillo-Negrete del, E. Scalas, E.W. Montroll, Fernando Falceto, G. Jona-Lasinio, G. Jona-Lasinio, G. Zaslavsky, H.C. Fogedby, I. Podlubny, I.A. Ibragimov, Iván Calvo, J. Aaronson, J. Honkonen, J.-P. Bouchaud, J.A. Mier, José G. Esteve, Juan C. Cuchí, L. Koralov, P. Lévy, R. Metzler, R. Sánchez, W. Rudin   +24 more
core   +1 more source

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

FEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine, Matteo Mucci, Antonio Recchiuti, Domenico Mattoscio   +3 more
wiley   +1 more source

On the nature of the new group LB1 [PDF]

arXiv, 2013
The new local group LB1 introduced previously will be studied in detail, depicting its unique nature that makes it a new group in fundamental physics. It will be made clear that even though most of its elements are Lorentz transformations, one unique discrete transformation not present in the Lorentz groups, is making this group into a new group.
arxiv  

SISO Output Affine Feedback Transformation Group and Its Faa di Bruno Hopf Algebra

, 2017
The general goal of this paper is to identify a transformation group that can be used to describe a class of feedback interconnections involving subsystems which are modeled solely in terms of Chen-Fliess functional expansions or Fliess operators and are
Ebrahimi-Fard, Kurusch, Gray, W. Steven
core   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

The New ‘Golden Age’ of Dentistry: A Highly Desirable Profession with Unprecedented Global Opportunities in Industry Settings

Journal of the California Dental Association
Background Dentistry 1.0, an era where the patient journey was embedded in fully analog realities gave way to a 2.0 era of select digitalization since the late 1990s. Now, we are arguably at another tipping point, where for the foreseeable future digital
Artemiz Seif, Christian R. Jarry, Amélie Michèle Chauvel   +2 more
doaj   +1 more source

Quantum group covariant systems

, 1995
The meaning of quantum group transformation properties is discussed in some detail by comparing the (co)actions of the quantum group with those of the corresponding Lie group, both of which have the same algebraic (matrix) form of the transformation ...
Chaichian, M., Kulish, P. P.
core   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source