Results 61 to 70 of about 1,672,113 (290)

Darboux transformation and multi-soliton solutions of Two-Boson hierarchy

, 2010
We study Darboux transformations for the two boson (TB) hierarchy both in the scalar as well as in the matrix descriptions of the linear equation. While Darboux transformations have been extensively studied for integrable models based on $SL(2,R)$ within
Ablowitz M. J., ASHOK DAS, Darboux G., Dodd R. K., Drinfeld V. G., Lamb G. L., U. SALEEM   +6 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Investigating the Difference in Mechanical Stability of Retained Austenite in Bainitic and Martensitic High-Carbon Bearing Steels using in situ Neutron Diffraction and Crystal Plasticity Modeling

Metals, 2019
In situ neutron diffraction of the uniaxial tension test was used to study the effect of the surrounding matrix microstructure on the mechanical stability of retained austenite in high-carbon bearing steels.
Rohit Voothaluru, Vikram Bedekar, Dunji Yu, Qingge Xie, Ke An, Praveen Pauskar, R. Scott Hyde   +6 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Matrix transformations of some sequence spaces [PDF]

Pacific Journal of Mathematics, 1969
This paper is a continuation of [1]. We begin with the notations for the sequence spaces considered in this paper. Let Γ be the space of sequences x = {xp} of complex numbers such that |xp|1/p⃗0 as p⃗∞. Γ can also be regarded as the space of integral functions f(z) = .
openaire   +6 more sources

Stochastic determination of matrix determinants

, 2015
Matrix determinants play an important role in data analysis, in particular when Gaussian processes are involved. Due to currently exploding data volumes, linear operations - matrices - acting on the data are often not accessible directly but are only ...
Dorn, Sebastian, Enßlin, Torsten A.
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Selective Downsampling for Fast and Accurate 3D Global Registration with Applications in Medical Imaging

Mathematics
Robust global point-cloud registration remains a key challenge in robotic neurosurgery, particularly for markerless patient registration, where anatomical surface acquisition can be incomplete and noisy. This paper proposes practical pre-processing steps,
Roč Stilinović, Marko Švaco, Bojan Šekoranja, Filip Šuligoj   +3 more
doaj   +1 more source