Results 51 to 60 of about 704,600 (271)
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Transformation optics in orthogonal coordinates
The author proposes the methodology of transformation optics in orthogonal coordinates to obtain the material parameters of the transformation media from the mapping in orthogonal coordinates. Several examples are given to show the applications of such a
Chen, Huanyang
core +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
On-Board Ortho-Rectification for Images Based on an FPGA
The traditional ortho-rectification technique for remotely sensed (RS) images, which is performed on the basis of a ground image processing platform, has been unable to meet timeliness or near timeliness requirements.
Guoqing Zhou Rongting Zhang Na Liu Jingjin Huang and Xiang Zhou +4 more
doaj +1 more source
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Measuring robot kinematics description and its workspace
Text deals with 6 degree of freedom measuring robot kinematics description enabling manipulation with measuring effector in 3D space. Mentioned description flowing from Denavit- Hartenberg notation for serial ordering of ideally stiff bodies connected by
Úředníček Zdeněk, Drga Rudolf
doaj +1 more source
The article presents the results of an analysis of the accuracy of the transformation of the coordinates of the boundary points of neighbouring mining areas in Silesia.
Monika Żogała
doaj +1 more source
Transformations of coordinates and Hamiltonian formalism in deformed Special Relativity
We investigate the transformation laws of coordinates in generalizations of special relativity with two observer-independent scales. The request of covariance leads to simple formulas if one assumes noncanonical Poisson brackets, corresponding to ...
G. Amelino-Camelia +16 more
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source

