From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Tomb at Abusir South from a time of change belonging to Ankhires, inspector of hairdressers of the Great House (AS 98) [PDF]
Pražské Egyptologické Studie, 2018 A new tomb (AS 98) of Ankhires, inspector of hairdressers of the Great House, was excavated at Abusir South in the autumn seasons of 2016 and 2017.
Veronika Dulíková +4 more
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FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Other title: Office of Children Services Transformation initial findings report
, 2020 "February 2020."; "Mike DeWine, Governor of Ohio; Jon Husted, Lt. Governor of Ohio."; "Ohio Governor's Children's Initiative, Children Services Transformation."; "Safe children. Stable homes.
Ohio. Children Services Transformation Advisory Council
core
Čtyři domy z města mrtvých. Předběžná zpráva o výzkumu komplexu hrobek AS 103 pod chrámem z Nové říše v jižním Abúsíru // Four houses from the city of the dead. Preliminary report on excavations of a complex of tombs, AS 103, under the New Kingdom temple at Abusir South [PDF]
Pražské Egyptologické Studie, 2018 In November 2017, mud brick structures, designated as AS 103, were excavated (fig. 1) in the area of the southeastern part of the later New Kingdom temple (numbered as structures AS 70–73; fig. 2).
Martin Odler +2 more
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The transformation of citizenship in complex societies [PDF]
Journal of Classical Sociology, 2010 The main purpose of this paper is to propose a theoretical framework for understanding the transformation of citizenship in complex societies. To this end, the paper is divided into six sections. The first section elucidates the main reasons for the renaissance of the concept of citizenship in the contemporary social sciences. The second section argues
openaire +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Technological Progress and the Transformation of Society: Perspectives for Individual Development
Perspective PoliticeThe presented contribution deals with the impact of technological progress on the transformation of society and its potential perspectives for the individual development of individuals.
Zuzana DRAKOVÁ
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Вестник Кемеровского государственного университета, 2014 The paper discusses the authors’basic positions in the book «Vehi» and compares them to the contemporary context. The issues related to the reconstruction of society are proved to be timeless and to demand perfection of each individual, both in the 20th ...
S. V. Zarutskaya
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