Results 71 to 80 of about 2,586,842 (344)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Cultural and educational background of formation of sustainable lifestyle [PDF]

open access: yes, 2013
In the XXI century mankind has approached the global transformation of society, which resulted in creation of a qualitatively new socioeconomic system, which is the knowledge society and the informational society, the foundation of which is the "economy ...
Jubran, J., Syukhina, A.G.
core  

From Sigmund Freud to Michel Foucault: a study on sexuality [PDF]

open access: yes, 2016
The studies on sexuality have been numerous over time, from the first analysis of the nineteenth century psychiatry to the accurate remarks of Michel Foucault.
Tomei, Gianfranco
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Contemporary challenges of the information society

open access: yesJournal of Modern Science, 2023
Objectives The aim of the work is to analyze the extremely dynamic changes in the perception of the information society. On the one hand, we are dealing with enormous technical and technological progress, which is caused by automation and robotization in
Waldemar Grądzki
doaj   +1 more source

The transformation of citizenship in complex societies [PDF]

open access: yesJournal of Classical Sociology, 2010
The main purpose of this paper is to propose a theoretical framework for understanding the transformation of citizenship in complex societies. To this end, the paper is divided into six sections. The first section elucidates the main reasons for the renaissance of the concept of citizenship in the contemporary social sciences.
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

THE ACTUAL THEMES OF «VEKHI»

open access: yesВестник Кемеровского государственного университета, 2014
The paper discusses the authors’basic positions in the book «Vehi» and compares them to the contemporary context. The issues related to the reconstruction of society are proved to be timeless and to demand perfection of each individual, both in the 20th ...
S. V. Zarutskaya
doaj  

Transformation of the consumption paradigm in modern Russian society

open access: yesНаука. Культура. Общество, 2023
The purpose of this study was to identify the main trends in the transformation of consumer preferences of Russians, which have recently been largely associated with the pandemic situation inside the country, the unprecedented influence of exogenous and ...
Elena I. Medvedeva   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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