Results 91 to 100 of about 2,586,842 (344)

THE IMPACT OF INFORMATION AND COMMUNICATION TECHNOLOGIES (ICT) ON THE DIGITAL TRANSFORMATION OF SOCIETY: A SOCIO-PHILOSOPHICAL ANALYSIS

open access: yesОсвітній дискурс
Urgency of the research. Information and communication technologies (ICTs) play a fundamental role in the digital transformation of society, changing the way we do business, communicate and govern.
Andrii Krupa, Victoriya Marienko
doaj   +1 more source

Redox Cycling Driven Transformation of Layered Manganese Oxides to Tunnel Structures.

open access: yesJournal of the American Chemical Society, 2020
Mn oxides are among the most ubiquitous minerals on Earth and play critical roles in numerous elemental cycles in biotic/abiotic loops as the key redox center.
Haesung Jung   +9 more
semanticscholar   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Knowledge and Power of the Civil Society: an empirical study of Brazilian professionals working in the NGOs [PDF]

open access: yes, 2016
This study critically analyses the way Non-Governmental Organizations (NGOs) operate in Brazil and their contribution to the development of the Brazilian civil society.
dos Santos de Sousa Teodosio, Armindo   +2 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Wittgenstein and the Old Testament

open access: yesReligions
I start this paper by giving a general account of Wittgenstein’s relationship to the Bible, especially to the Old Testament. I will then examine those passages in his work where he explicitly refers to the Old Testament.
Esther Heinrich
doaj   +1 more source

The European Union, Conflict Transformation and Civil Society: A Conceptual Framework [PDF]

open access: yes
The European Union considers conflict resolution as a cardinal objective of its foreign policy. It makes use of a number of policy instruments to promote conflict transformation through ‘constructive engagement’, which cover a range of sectors affecting ...
Nathalie Tocci
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

The European Union, Civil Society and Conflict Transformation [PDF]

open access: yes
The European Union considers conflict resolution as a cardinal objective of its foreign policy. It makes use of a number of policy instruments to promote conflict transformation through ‘constructive engagement’, which cover a range of sectors affecting ...
Nathalie Tocci
core  

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