Results 111 to 120 of about 2,586,842 (344)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Evolving spatialities of digital life: Troubling the smart city/home divide
Digital Geography and SocietyWhile feminist geographers have long aimed to trouble conceptions of the city/home (and, by extension, public/private) divides, the digital city and the digital home are still often theorized as separate phenomena within much digital geography literature.
Casey R. Lynch, Miriam E. Sweeney
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
About the transformation of Japanese society
Японские исследованияSince the late 1990s, under conditions of economic depression and the aggravation of a number of unfavorable social trends (population aging, shrinking of youth population, and declining birth rates), there has been a rapid spread of the idea that ...
I. P. Lebedeva
doaj +1 more source
Coming Too Late? The EU’s Mixed Approaches to Transforming the Israeli-Palestinian Conflict [PDF]
As is well known, the amount of aid given by international donors both to Israel and to the occupied Palestinian Territories (oPt) is unparalleled in the world, but the fact that people can turn violent against their own CSOs trying to promote ...
Benoit Challand
core
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
An Analysis of the Quantum Penny Flip Game using Geometric Algebra
, 2009 We analyze the quantum penny flip game using geometric algebra and so determine all possible unitary transformations which enable the player Q to implement a winning strategy.
Benjamin S. C. +22 more
core +2 more sources
Community action for sustainable housing: Building a low-carbon future [PDF]
, 2009 This paper presents a new analytical framework of 'grassroots innovations' which views community-led initiatives for sustainable development as strategic green niches with the potential for wider transformation of mainstream society.
Berkhout +41 more
core +1 more source