Results 51 to 60 of about 193,312 (244)

Collimating lenses from non-Euclidean transformation optics

, 2012
Based on the non-Euclidean transformation optics, we design a thin metamaterial lens that can achieve wide-beam radiation by embedding a simple source (a point source in three-dimensional case or a line current source in two-dimensional case). The scheme
Huanyang Chen, Kan Yao, Kwon D-H, Leonhardt U, Leonhardt U, Luneburg R K, Miñano J C, Xunya Jiang   +7 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Shaping soliton properties in optical Mathieu lattices

, 2005
We address basic properties and stability of two-dimensional solitons in photonic lattices induced by the nondiffracting Mathieu beams. Such lattices allow for smooth topological transformation of radially symmetric Bessel lattices into quasi-one ...
Alexey A. Egorov, Chavez-Cerda, Efremidis, Fleischer, Fleischer, Fleischer, Gutierrez-Vega, Gutierrez-Vega, Kartashov, Kartashov, Kartashov, Kartashov, Lluis Torner, Martin, Neshev, Neshev, Victor A. Vysloukh, Xu, Xu, Yang, Yang, Yaroslav V. Kartashov   +21 more
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

A differential geometry approach to asymmetric transmission of light

, 2017
In the last ten years, the technology of differential geometry, ubiquitous in gravitational physics, has found its place in the field of optics. It has been successfully used in the design of optical metamaterials, through a technique now known as ...
Asenjo, Felipe A., Erices, Cristián, Gomberoff, Andrés, Hojman, Sergio A., Montecinos, Alejandra   +4 more
core   +1 more source

Inverse problem in transformation optics [PDF]

Journal of Optics, 2011
The straightforward method of transformation optics implies that one starts from the coordinate transformation, determines the Jacobian matrix, the fields and material parameters of the cloak. However, the coordinate transformation appears as an optional function: it is not necessary to know it. We offer the solution of some sort of the inverse problem:
openaire   +4 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Investigation of the Uniformity of Gel Shrinkage by Imaging Tracer Particles Using X‐Ray Microtomography

Advanced Engineering Materials, EarlyView., 2023
A novel method for tracking structural changes in gels using widely accessible microcomputed tomography is presented and validated for various hydro‐, alco‐, and aerogels. The core idea of the method is to track positions of micrometer‐sized tracer particles entrapped in the gel and relate them to the density of the gel network.
Anja Hajnal, Mimololorun Lucy Aiyelari, Martin Dirauf, Pavel Gurikov   +3 more
wiley   +1 more source

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

An omnidirectional retroreflector based on the transmutation of dielectric singularities

, 2009
In the field of transformation optics, metamaterials mimic the effect of coordinate transformations on electromagnetic waves, creating the illusion that the waves are propagating through a virtual space.
Leonhardt, Ulf, Ma, Yun Gui, Ong, C. K., Tyc, Tomas   +3 more
core   +1 more source