Results 121 to 130 of about 2,123,374 (298)

Features of Relaxation Processes During Martensitic Transformation

open access: yesУспехи физики металлов, 2005
The development of the new alloys, which undergo martensitic transformation, with the specified set of physical-mechanical properties cannot be realized without knowledge of the martensitic transformation.
Yu. M. Koval’
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Hitting properties and non-uniqueness for SDE driven by stable processes

open access: yes, 2011
We study a class of self-similar jump type SDEs driven by H\"older-continuous drift and noise coefficients. Using the Lamperti transformation for positive self-similar Markov processes we obtain a necessary and sufficient condition for almost sure ...
Berestycki, Julien   +3 more
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Diagnosis and treatment of skin T-cell lymphoma undergoing transformation in lymphosarcoma

open access: yesТерапевтический архив, 2009
Aim. To define complex of parameters characterizing transformation of skin T-cell tumors in lymphosarcoma; to show specific treatment of patients with this transformation. Material and methods.
Yuliya Eykhenovna Vinogradova   +13 more
doaj  

A method for generating distributions with an application to Cauchy distribution

open access: yesResearch in Statistics
There are numerous transformation methods which are in use right now. In this article, the newly proposed model is achieved by using the transformation method known as beta transformation where it does not require more than one additional parameters to ...
Fasna K.
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

On arithmetical and dynamical properties of Lorentz maps of the torus

open access: yes, 2004
We proved that any Lorentz transformation of 2-torus is Anosov automorphism. One completely describes admissible parameters of Lorentz transformations and their arithmetical properties.
Aranson, S., Zhuzhoma, E.
core   +1 more source

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