Results 121 to 130 of about 561,734 (311)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Transformation of surface waves over a bottom step

open access: yes, 2015
We analyze in detail the problem of the transformation of surface gravity waves over a bottom step in a basin of arbitrary depth in the linear approximation.
Kurkin, A. A.   +2 more
core   +1 more source

Features of Relaxation Processes During Martensitic Transformation

open access: yesУспехи физики металлов, 2005
The development of the new alloys, which undergo martensitic transformation, with the specified set of physical-mechanical properties cannot be realized without knowledge of the martensitic transformation.
Yu. M. Koval’
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Transformation of Biomass Theory to Practice

open access: yes, 2014
Biomass is a key resource for meeting the energy and material demands of mankind in the future. As a result, businesses and technologies are developing around biomass processing and its applications. Transformation of Biomass: Theory to Practice explores
Hornung, Andreas
core  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Diagnosis and treatment of skin T-cell lymphoma undergoing transformation in lymphosarcoma

open access: yesТерапевтический архив, 2009
Aim. To define complex of parameters characterizing transformation of skin T-cell tumors in lymphosarcoma; to show specific treatment of patients with this transformation. Material and methods.
Yuliya Eykhenovna Vinogradova   +13 more
doaj  

A method for generating distributions with an application to Cauchy distribution

open access: yesResearch in Statistics
There are numerous transformation methods which are in use right now. In this article, the newly proposed model is achieved by using the transformation method known as beta transformation where it does not require more than one additional parameters to ...
Fasna K.
doaj   +1 more source

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