Results 111 to 120 of about 1,989,040 (349)

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Approximate periodically focused solutions to the nonlinear Vlasov-Maxwell equations for intense beam propagation through an alternating-gradient field configuration

Physical Review Special Topics. Accelerators and Beams, 1999
This paper considers an intense non-neutral ion beam propagating in the z direction through a periodic-focusing quadrupole or solenoidal field with transverse focusing force, -[κ_{x}(s)xe[over ^]_{x}+κ_{y}(s)ye[over ^]_{y}], on the beam ions.
Ronald C. Davidson, Hong Qin, Paul J. Channell   +2 more
doaj   +1 more source

Additive Manufactured Metal-Only Modulated Metasurface Antennas

IEEE Transactions on Antennas and Propagation, 2018
In metasurface (MTS) antennas, a surface wave (SW) is gradually transformed into a leaky wave, owing to the SW interaction with a reactance tensor periodically modulated in the aperture plane.
D. González-Ovejero, N. Chahat, R. Sauleau, G. Chattopadhyay, S. Maci, M. Ettorre   +5 more
semanticscholar   +1 more source

Space Target Recognition of Radar Cross-Section Sequence Based on Transformer

Mathematics
As the strategic importance of space continues to grow, space target recognition technology is critical for advancing space surveillance systems, optimizing the use of space resources, and ensuring space security. In response to challenges in analyzing radar cross-section (RCS) sequences, we propose a deep learning-based method designed to enhance the ...
Meng Xie, Weiwei Wu, Chenchen Fu, Sujunjie Sun   +3 more
openaire   +2 more sources

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Hydrotreatment of pyrolysis bio-oil: A review

, 2019
Fast pyrolysis converts >60 wt% of lignocellulosic materials into bio-oil. The two-step bio-oil hydrotreatment concept has had a major impact in the development of bio-oil hydro-treatment.
Yinglei Han, Mortaza Gholizadeh, Chi-Cong Tran, S. Kaliaguine, Chun-Zhu Li, Mariefel V. Olarte, M. García-Pérez   +6 more
semanticscholar   +1 more source

Rectangular capture area to circular combustor scramjet engine [PDF]

A new concept for a scramjet engine design was presented. The inlet transformed a rectangular shaped capture stream into a cross section which was almost circular in shape at the inlet throat or combustor entrance. The inlet inner surface was designed by
Pinckney, S. Z.
core   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Out-of-Plane Vibration Analysis of Multiple-Stepped Circular Beam

European Mechanical Science, 2018
Stepped circular beams are widely used in various engineering fields. Thus, studying the free vibration characteristics of those structures is an essential subject of research.
Timuçin Alp Aslan, Beytullah Temel, Ahmad Reshad Noori   +2 more
doaj   +1 more source