Results 81 to 90 of about 6,234,342 (308)
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
This work presents a rigorous analysis of H‐polarised wave diffraction by a finite parallel‐plate waveguide cavity with perfect electric conductor loading, employing the Wiener‐Hopf technique.
Tong Zhang, Kazuya Kobayashi
doaj +1 more source
Stan's father Theopholis Cross [picture] /
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan's father Theopholis"--In ink, on verso.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.pic ...
Cross, Stan, 1888-1977.
core
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Development of the pile oscillation method for the determination of integral cross section data at the AKR-2 training and research reactor [PDF]
The development of Generation-IV reactors requires validated low uncertainty nuclear data for novel materials. To address this, the pile oscillation method for measuring integral absorption cross sections has been developed at the AKR-2 research reactor ...
Knospe Alexander +4 more
doaj +1 more source
Wally and the Major [picture] : at cross purposes /
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross 7/87"--In ink, lower right. "8335 Thur Apr 13 At Cross Purposes"--In ink, right margin; "8335"--In pencil, upper right corner.; Also available in an electronic ...
Cross, Stan, 1888-1977.
core
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Wally and the Major [picture] : at cross purposes /
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross 9/80"--In ink, lower right. "8953 Tue Apr 8. At Cross Purposes"--In ink, right margin; "8953"--In pencil, upper right corner.; Also available in an electronic ...
Cross, Stan, 1888-1977.
core
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
IMPACTO DOS INVESTIMENTOS EM TI NO RESULTADO OPERACIONAL DOS BANCOS BRASILEIROS [PDF]
IT has transformed the banking industry in recent years, it has become strategic and vital for business. Given this context, thefollowing main objective was to analyze the impact of IT investments in operating income of these banks. The econometric model
Fernando de Abreu Faria +1 more
doaj

