Results 81 to 90 of about 677,995 (332)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Analysis and engineering calculation of excitation inrush current characteristics of high voltage built-in high impedance transformer

Diance yu yibiao
This paper presents a calculation scheme of inrush current of high voltage built-in high impedance transformer which takes into account the nonlinear changes of remanence and excitation inductance.
RONG Chunyan, HU Shiyao, LI Teng, SU Zhonghuan, CHENG Rong, WANG Guijuan   +5 more
doaj   +1 more source

Influence of thermal aging on dielectric characteristics of transformer insulating oils [PDF]

E3S Web of Conferences
Transformer oil is a liquid insulating material used in transformers as insulation and coolant. Particular characteristics insulating oil materials must be able to withstand breakdown voltages, while transformer oil as a coolant must be able to minimize ...
Saodah Siti, Eliana Bella, Jakariya
doaj   +1 more source

Transformer Neural Networks Attending to Both Sequence and Structure for Protein Prediction Tasks [PDF]

, 2022
Anowarul Kabir, Amarda Shehu
openalex   +1 more source

Transforming vaccinology

Cell
The COVID-19 pandemic placed the field of vaccinology squarely at the center of global consciousness, emphasizing the vital role of vaccines as transformative public health tools. The impact of vaccines was recently acknowledged by the award of the 2023 Nobel Prize in Physiology or Medicine to Katalin Kariko and Drew Weissman for their seminal ...
Rino Rappuoli, Galit Alter, Bali Pulendran   +2 more
openaire   +3 more sources

Appell Transformation and Canonical Transforms [PDF]

Symmetry, Integrability and Geometry: Methods and Applications, 2011
The interpretation of the optical Appell transformation, as previously elaborated in relation to the free-space paraxial propagation under both a rectangular and a circular cylindrical symmetry, is reviewed. Then, the caloric Appell transformation, well known in the theory of heat equation, is shown to be amenable for a similar interpretation involving
openaire   +5 more sources

Character-level Transformer-based Neural Machine Translation

, 2020
Neural machine translation (NMT) is nowadays commonly applied at the subword level, using byte-pair encoding. A promising alternative approach focuses on character-level translation, which simplifies processing pipelines in NMT considerably.
Banar, Nikolay, Daelemans, Walter, Kestemont, Mike   +2 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Ultrasonic localization method based on Chan‐WLS algorithm for detecting power transformer partial discharge faults by fibre optic F‐P sensing array

High Voltage
Fibre optic F‐P sensor has become one of the mainstream detection methods for partial discharge faults due to their advantages of good insulation, high sensitivity, resistance to electromagnetic interference, simple structure and inexpensive pricing. The
Hong Liu, Tianhe Yang, Zhixian Zhang, Haoyuan Tian, Yuxuan Song, Qiuxia Sun, Wei Wang, Yunjun Geng, Weigen Chen   +8 more
doaj   +1 more source