Results 111 to 120 of about 85,416 (307)
Applied SciencesKeeping drinking water safe is a critical aspect of protecting public health. Traditional laboratory-based methods for evaluating water potability are often time-consuming, costly, and labour-intensive.
Enes Algül +6 more
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Relaxed Attention for Transformer Models
, 2022 The powerful modeling capabilities of all-attention-based transformer architectures often cause overfitting and - for natural language processing tasks - lead to an implicitly learned internal language model in the autoregressive transformer decoder ...
Fingscheidt, Tim +3 more
core
Remote SensingObject detection is essential for precision agriculture applications like automated plant counting, but the minimum dataset requirements for effective model deployment remain poorly understood for arable crop seedling detection on orthomosaics.
Samuele Bumbaca, Enrico Borgogno-Mondino
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Deconstructing a Minimalist Transformer Architecture for Univariate Time Series Forecasting
AlgorithmsThis paper provides a detailed breakdown of a minimalist, fundamental Transformer-based architecture for forecasting univariate time series. It describes each processing step in detail, from input embedding and positional encoding to self-attention ...
Filippo Garagnani, Vittorio Maniezzo
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
InformationLoss functions play a significant role in shaping model behavior in machine learning, yet their design implications remain underexplored in natural language processing tasks such as Named Entity Recognition (NER).
Sonia Pascua, Michael Pan, Weimao Ke
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source